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Autoimmune Diseases Brain Health Cardiovascular Health Metals Microbes Women’s Health

Conditions

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Alzheimer’s Dementia Anemia Autism spectrum disorder (ASD) Bacterial Vaginosis Breast Cancer Chronic Pelvic Pain (CPP) Diabetes Type I Endometriosis Erectile Dysfunction Graves Disease Hashimoto’s Thyroiditis Heart Failure Infertility Irritable Bowel Syndrome (IBS) Parkinson’s Disease

Definitions

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Amsel Criteria Blood-Brain Barrier (BBB) Bradford Hill Criteria Coelomic Metaplasia Theory Drug Repurposing  Endometriomas Environmental Theory of Endometriosis Estrobolome Estrogen Estrogen Receptors (ER) Facultative Anaerobes Fecal Microbiota Transplantation (FMT) Genetic and Epigenetic Theory of Disease Gram-Negative Bacteria Idiopathic

Guides & Resources

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Endometriosis Guide Microbiome Diet for Endometriosis

Interventions

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Boric Acid Cholestyramine Clindamycin Clinoptilolite Zeolite Dimethylglyoxime (DMG) Hyperbaric Oxygen Therapy (HBOT) Lactoferrin Low‑Nickel Diet (LNiD) Lugdunin Metformin Metronidazole Phage Therapy Photobiomodulation Probiotics Tinidazole

Supplements

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Essential Oils Flavones and Flavonols Guar Gum Pueraria Flower Extract (PFE)

Microbes

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Escherichia coli (E. coli) H pylori Pseudomonas aeruginosa Staphylococcus aureus (S. Aureus) Streptococcus agalactiae (GBS) Streptococcus spp. Ureaplasma urealyticum (U. urealyticum)

Metals

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Gallium Metalloestrogens Nickel Nickel in Escherichia coli: Metabolic and Pathogenic Roles Zinc

Research Feeds

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Maternal Iron Deficiency Anemia Affects Postpartum Emotions and Cognition The Key Element Role of Metallophores in the Pathogenicity and Virulence of Staphylococcus aureus: A Review The effectiveness of iron supplementation for postpartum depression Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors 1H NMR- based metabolomics approaches as non-invasive tools for diagnosis of endometriosis A Comparative Study of Blood Levels of Manganese, Some Macroelements and Heavy Metals in Obese and Non-Obese Polycystic Ovary Syndrome Patients A Comparative Study of the Gut Microbiota Associated With Immunoglobulin a Nephropathy and Membranous Nephropathy A comparative study of the gut microbiota in immune-mediated inflammatory diseases-does a common dysbiosis exist? A comparative study of the gut microbiota in immune-mediated inflammatory diseases-does a common dysbiosis exist? A comprehensive analysis of breast cancer microbiota and host gene expression A comprehensive analysis of breast cancer microbiota and host gene expression A Comprehensive Review on Postpartum Depression A cross-sectional analysis about bacterial vaginosis, high-risk human papillomavirus infection, and cervical intraepithelial neoplasia in Chinese women A cross-sectional pilot study of birth mode and vaginal microbiota in reproductive-age women A metabonomics approach as a means for identification of potentialbiomarkers for early diagnosis of endometriosis

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June 30, 2021

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Last Updated: June 30, 2021

Microbiome Signatures identifies and validates condition-specific microbiome shifts and interventions to accelerate clinical translation. Our multidisciplinary team supports clinicians, researchers, and innovators in turning microbiome science into actionable medicine.

Karen Pendergrass

Karen Pendergrass is a microbiome researcher specializing in microbiome-targeted interventions (MBTIs). She systematically analyzes scientific literature to identify microbial patterns, develop hypotheses, and validate interventions. As the founder of the Microbiome Signatures Database, she bridges microbiome research with clinical practice. In 2012, based on her own investigative research, she became the first documented case of FMT for Celiac Disease—four years before the first published case study.

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