Divine Aleru, Microbiome Signatures Research Coordinator

A bibliometric analysis of dysmenorrhea research from 1992 to 2022 reveals increasing global interest in its pathogenesis, treatment, and functional connectivity. It emphasizes the role of prostaglandins, nonsteroidal anti-inflammatory drugs, and traditional Chinese medicine in managing the condition.

Primary dysmenorrhea is a common and impactful condition affecting young women. This review explores its pathophysiology, symptoms, and treatment options to improve diagnosis and management in clinical practice.

Primary dysmenorrhea is a common, underdiagnosed condition that causes significant pain and affects women’s daily lives. The study highlights its pathophysiology, diagnostic approach, treatment options, and the need for greater awareness and research into its management.

Primary dysmenorrhea (D) is painful menstrual cramps without underlying pelvic pathology, predominantly caused by elevated prostaglandins inducing uterine contractions and ischemia. Managing primary dysmenorrhea (D) requires understanding its complex mechanisms involving prostaglandins, oxidative stress, and inflammation. Treatments include SAIDs, hormonal therapies, and promising complementary options like probiotics, vitamins, omega-3 fatty acids, exercise, yoga, acupuncture, and massage, significantly improving women’s quality of life.

What was studied?This study examined the interaction between the vaginal microbiota and mycobiota in patients with vulvovaginal candidiasis (VC). The research focused on understanding the role of different Candida species, specifically Candida albicans and Candida glabrata, in the pathology of VC, and how they influence the vaginal bacteriome. The study aimed to identify the microbial […]

This study investigates the link between gut microbiota and postpartum depressive disorder (PD), identifying specific microbiota changes that correlate with depressive symptoms and hormonal levels. These findings could provide biomarkers for diagnosing and treating PD.

This study explores the differences in microbiomes across breast tissue, oral, and urinary sites in women with and without breast cancer. Key findings suggest distinct microbiomic patterns in cancerous tissue and the urinary microbiome, providing new insights into the role of microbiota in cancer development.

This study examined the impact of estrogen on oral health and microbiome composition in OVID-19 patients, showing that postmenopausal women and men experience poorer oral health, which correlates with elevated proinflammatory cytokines and lower CE2 expression, potentially influencing OVID-19 outcomes.

This study explores the impact of vaginal microbiota on VF outcomes in women with infertility. It highlights how specific bacteria like Lactobacillus iners and Pseudomonas spp. can predict VF success or failure, offering potential insights for personalized RT treatments.

This pilot study links gut microbiome diversity with breast cancer risk factors and tumor characteristics, particularly in ER2+ tumors and those with early menarche. It suggests microbial alterations in these groups that may influence cancer development and risk.