Divine Aleru, Microbiome Signatures Research Coordinator

The article redefines menopausal hot flashes as signs of underlying neurovascular dysregulation, linking them to chronic conditions like cardiovascular disease and cognitive decline. It advocates for more targeted, personalized treatments and further research into the physiological mechanisms behind these symptoms.

The review explores the physiological mechanisms behind menopausal hot flashes, including thermoregulatory changes, sympathetic nervous activation, and estrogen depletion. It also examines treatments such as clonidine and behavioral therapies.

What was reviewed?The article presents a detailed review of menopausal hot flashes, examining both the physiological and biosociocultural factors that contribute to this common menopausal symptom. It highlights the lack of clarity regarding the exact causes and mechanisms of hot flashes, despite decades of research. The paper discusses how the understanding of hot flashes has […]

This review synthesizes current evidence on menopausal hot flashes, focusing on neuroendocrine mechanisms, genetic factors, and a stepwise, personalized treatment approach, emphasizing new targets such as the NDy neuronal system and GRP for future therapies.

Hibiscus rosa-sinensis shows potent antifertility effects through antiovulatory, antiimplantation, and antispermatogenic mechanisms in animal studies, supporting its development as a safe, natural contraceptive pending further research.

This review highlights Hibiscus rosa-sinensis as a potent medicinal plant with diverse pharmacological activities linked to its rich phytochemical profile, underscoring its therapeutic potential and the need for further clinical research.

The ethanolic root extract of Hibiscus rosa-sinensis shows potent, reversible post-coital antifertility effects in rats via estrogenic mechanisms, supporting its potential as a safe herbal contraceptive.

Hibiscus rosa-sinensis exhibits significant antifertility effects in animal models through antiovulatory, antiimplantation, and spermatogenic disruption mechanisms, highlighting its potential as a safe, reversible herbal contraceptive pending further research.

Routine consumption of hibiscus tea or juice may affect female fertility by disrupting ovulation, implantation, and hormonal balance. Women trying to conceive or undergoing fertility treatments should be cautious and discuss herbal intake with their healthcare provider to avoid unintended reproductive consequences.

A case report highlights hibiscus tea’s phytoestrogens potentially lowering VT risk while interfering with VF hormone therapy, emphasizing a need for cautious use and further research.