Divine Aleru, Microbiome Signatures Research Coordinator

This case-control study highlights the significant role of diet in ovarian cancer risk, with high vegetable and fruit intake reducing risk, while animal fats and salted vegetables increase it. Fried and smoked foods also contribute to a higher risk.

This review underscores the importance of diet and physical activity in modulating the gut microbiome of cancer patients. Diets like fiber-rich and Mediterranean diets show promise in improving cancer treatment outcomes. Exercise also enhances microbial diversity and immune function, potentially improving patient quality of life.

Probiotics were shown to significantly reduce cancer cell proliferation, promote apoptosis, and inhibit migration in breast and ovarian cancer cells, suggesting their potential as adjunctive cancer therapies.

This review maps advances in ovarian cancer management, from surgery and chemotherapy to targeted and emerging therapies, and highlights a need to integrate microbiome insights.

This review analyzes the global epidemiology and risk factors of ovarian cancer, emphasizing the role of genetic predispositions, reproductive factors, and lifestyle choices. It highlights the disparities in incidence and mortality rates across regions and calls for better prevention and early detection strategies.

This review discusses ovarian cancer diagnosis, molecular characteristics, and treatment strategies, emphasizing the role of targeted therapies like ARP inhibitors and immunotherapy, with a focus on personalized treatment approaches based on genetic and molecular tumor profiles.

This review covers the epidemiology, genetics, and molecular mechanisms of ovarian cancer, focusing on the role of estrogen receptors and genetic mutations such as RCA1/2. It emphasizes the importance of genetic testing and the potential of targeted therapies, including ARP inhibitors, for improving patient outcomes.

This review discusses liquid biopsy techniques for early ovarian cancer detection, focusing on circulating tumor cells, cell-free NA, and extracellular vesicles. It highlights their potential to improve sensitivity, specificity, and prognosis prediction, providing a promising avenue for non-invasive cancer screening.

This review explores the molecular mechanisms of ovarian cancer metastasis, focusing on the role of stromal cells and the metastatic routes—passive dissemination and hematogenous spread—while discussing therapeutic implications for targeting both cancer cells and the tumor microenvironment.

Ovarian cancer (C) remains one of the most deadly cancers affecting women, with an estimated 320,000 new cases diagnosed worldwide annually, making it the eighth most commonly diagnosed cancer. It also accounts for over 200,000 deaths each year, reflecting its high lethality. The disease is often diagnosed at advanced stages (stage II and V) due […]