Divine Aleru, Microbiome Signatures Research Coordinator

This study used a multi-omic approach to reveal key microbial and metabolic markers of bacterial vaginosis. It identified two distinct symptomatic V metabotypes, each defined by unique microbial and metabolite associations, underscoring the need for metabolomics-informed clinical diagnostics.

This study highlights metabolic interactions between Gardnerella vaginalis and Prevotella bivia, revealing their role in bacterial vaginosis and preterm birth risk. Using MR metabolomics, it identifies acetate as a key metabolite linked to vaginal dysbiosis, offering insights for improving V diagnostics and potential microbiome-targeted interventions.

A nutrient-rich diet lowers bacterial vaginosis (V) risk, while processed foods increase it. This study highlights the importance of dietary choices in vaginal microbiome balance, offering insights for clinicians on how diet influences V risk.

A high glycemic load diet increases bacterial vaginosis (V) risk, while nutrient-rich diets lower it. This study highlights the link between diet quality and vaginal microbiome balance, providing insights for clinicians on how dietary interventions may help prevent V.

A diet high in processed foods and sugar increases bacterial vaginosis (V) risk, while a plant-based diet lowers it. This study highlights the importance of dietary choices in vaginal health, providing insights for clinicians on how nutrition influences the vaginal microbiome.

Higher dietary fat intake increases the risk of bacterial vaginosis (V), while folate, vitamin E, and calcium may lower severe V risk. This study suggests dietary interventions could play a role in managing V, offering insights for clinicians on how nutrition affects vaginal microbiome balance.

The Nugent Score is a standardized Gram stain-based scoring system used to diagnose bacterial vaginosis (V) by assessing key bacterial morphotypes in vaginal samples. With its high specificity, it remains a gold standard in microbiome research, though its complexity and need for trained personnel make it less common in routine clinical practice.

Amsel’s Criteria is a clinically established diagnostic method for bacterial vaginosis, offering a practical and accessible alternative to laboratory-based approaches. It evaluates four key clinical indicators, ensuring timely diagnosis and intervention in outpatient settings.

This study analyzed daily changes in vaginal microbiota before, during, and after V episodes. Findings highlight microbial instability, early dysbiosis markers, and the need for microbiome-focused V treatments.

This study assessed vaginal microbiota in V-positive women using real-time CR. It found reduced Lactobacillus crispatus, biofilm-associated pathogens, and high diagnostic accuracy for molecular testing. Results suggest CR-based diagnostics improve V detection and highlight the need for microbiome-targeted therapies.