Giorgos Aristotelous

This study reveals that Graves’ disease patients exhibit distinct gut microbiota signatures, with increased Bacteroidetes and Prevotellaceae and decreased Firmicutes and Lachnospiraceae, strongly associated with thyroid function markers. These microbial shifts may play a role in D pathogenesis and serve as potential clinical biomarkers.

This study identified distinctive alterations in gut microbiota in Graves’ disease, including reduced diversity and specific taxonomic shifts. Key microbial signatures correlated with thyroid autoimmunity, highlighting potential diagnostic biomarkers and suggesting that microbiome modulation may offer new therapeutic avenues for Graves’ disease.

This study reveals that Chinese Graves’ disease patients exhibit reduced gut microbiota diversity and distinct compositional changes, with specific genera correlating to disease markers. Anti-thyroid therapy partially restores microbiome diversity, suggesting gut microbial signatures may serve as biomarkers or therapeutic targets in Graves’ disease.

This study demonstrates that gut microbiome composition and function differ significantly between Graves’ disease and Graves’ orbitopathy, with specific taxa correlating with thyroid autoimmunity. These findings highlight the potential of gut microbial markers for distinguishing O from D and understanding disease mechanisms.

This study found that Graves’ disease is associated with reduced gut microbial diversity and specific increases in Bacilli, Lactobacillales, Prevotella, Megamonas, and Veillonella, alongside decreases in Ruminococcus, Rikenellaceae, and Alistipes, identifying a distinctive intestinal microbiota signature relevant to D pathogenesis.

This systematic review found insufficient evidence to confirm that physical exercise reduces endometriosis risk or symptoms, though some data suggest a potential protective effect. Well-designed controlled trials are needed to clarify the role of exercise in endometriosis prevention and management.

Resistance (strength) training appears to exert modest but meaningful effects on the human gut microbiome. Unlike aerobic exercise, which often leads to pronounced changes in microbial diversity and taxonomic shifts, short-term resistance training tends to result in minimal changes in overall microbiome composition or alpha-diversity. However, this does not indicate a lack of functional impact. […]

This review found that physical activity and exercise significantly improved pain, emotional well-being, and perceived control in women with endometriosis, supporting their use as safe and effective complementary therapies.

Moderate physical activity was associated with improved thyroid function and reduced thyroid autoimmunity in a large Korean cohort, especially in women and individuals with elevated MI.

This study found that a structured exercise program in euthyroid Graves’ disease patients improved aerobic capacity, reduced fatigue, normalized some thyroid hormones, accelerated anti-thyroid medication withdrawal, and reduced relapse rates, highlighting exercise’s clinical and potential immunological benefits.