Research feed 
Overview 
Microbiome Signature 
Interventions 
FAQs 
Research Feed 
Update History 
References Osteoporosis affects one in three women over 50. Estrogen decline during menopause accelerates bone loss, making weight-bearing exercises, calcium, and vitamin D essential for maintaining bone health. Early intervention can reduce fracture risk, and the gut microbiome may play a role in improving bone density.
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Menopausal Hot Flashes
Researched by:
-
Divine Aleru
ID
Divine Aleru
Read MoreI am a biochemist with a deep curiosity for the human microbiome and how it shapes human health, and I enjoy making microbiome science more accessible through research and writing. With 2 years experience in microbiome research, I have curated microbiome studies, analyzed microbial signatures, and now focus on interventions as a Microbiome Signatures and Interventions Research Coordinator.
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
-
Divine Aleru
Read More
Researched by:
-
Divine Aleru
ID
Divine Aleru
Read More
Microbiome Signatures identifies and validates condition-specific microbiome shifts and interventions to accelerate clinical translation. Our multidisciplinary team supports clinicians, researchers, and innovators in turning microbiome science into actionable medicine.
Divine Aleru
Overview
Menopausal hot flashes (HFs) are a common and disruptive symptom experienced by women transitioning through menopause, defined by sudden, intense sensations of heat, often accompanied by sweating, flushing, anxiety, and chills. It affects approximately 85% of menopausal women, with duration and severity varying widely by geography, genetics, and lifestyle.[1] These episodes usually last 1 to 5 minutes, and while estrogen depletion is a key factor in their onset, the exact mechanism remains elusive. The hypothalamus, responsible for regulating body temperature, becomes dysregulated during menopause, leading to an exaggerated response to small increases in core body temperature, causing excessive vasodilation and sweating.[2] Recent research has suggested that other factors, such as neurokinin B, serotonin, norepinephrine, and inflammation, may also contribute to the severity and frequency of hot flashes, further complicating their pathophysiology.[3] While these episodes are most common during perimenopause, they can persist for years after menopause, significantly impacting a woman’s quality of life, leading to sleep disturbances, mood changes, and increased anxiety.
Associated Conditions
Hot flashes are often linked with a range of comorbid conditions, particularly sleep disturbances such as chronic insomnia, as hot flashes occurring at night, also known as night sweats, disrupt sleep patterns.[4][5] Studies show that women with severe hot flashes are more likely to experience insomnia, which worsens the overall health impact of these vasomotor symptoms. The presence of hot flashes has been associated with increased risks of cardiovascular disease, metabolic syndrome, and osteoporosis.[6] The vasomotor instability caused by hot flashes can lead to endothelial dysfunction, increasing susceptibility to heart disease and contributing to poor lipid profiles.[7] The comorbidities linked to hot flashes highlight the need for a comprehensive approach to managing menopausal symptoms, taking into account both physical and emotional health.
Causes
The exact cause of menopausal hot flashes is not fully understood. Still, estrogen deficiency is considered the primary factor, as the decrease in estrogen during menopause disrupts the hypothalamic regulation of body temperature.[8] However, estrogen alone does not fully explain the onset or persistence of hot flashes, as the severity and frequency do not correlate directly with estrogen levels. Emerging theories suggest that neurovascular dysregulation plays a significant role, with the autonomic nervous system becoming overly sensitive to small increases in body temperature, triggering excessive vasodilation and sweating.[9] Additionally, neurotransmitter imbalances, particularly involving serotonin and norepinephrine, are believed to affect hypothalamic function and contribute to the thermoregulatory dysfunction seen in hot flashes. Inflammation, marked by elevated levels of pro-inflammatory cytokines like TNF-α and IL-8, has also been implicated in more severe hot flashes, suggesting that systemic inflammation may contribute to the severity of these symptoms.[10] However, these theories remain under investigation, with further research needed to confirm their exact role in the pathogenesis of hot flashes.
Diagnosis
Diagnosing hot flashes primarily relies on self-reports from patients, where they track the frequency and severity of episodes. In clinical settings, objective measures such as skin conductance, thermography, and skin temperature measurements are also used to validate self-reports.[11] These methods provide insight into the physiological changes that occur during a hot flash, such as increased sweating and blood flow to the skin. In recent years, biomarkers have been explored as potential diagnostic tools, with studies suggesting that elevated levels of inflammatory cytokines, such as TNF-α and IL-8, are associated with the severity of hot flashes.[12] While these objective markers hold promise for a more accurate diagnosis, further research is needed to establish reliable, non-invasive diagnostic methods for hot flashes. The inclusion of these biomarkers, along with improved patient tracking, could provide a more precise understanding of the condition’s severity and contribute to more targeted treatment approaches.
Primer
Hot flashes are a prominent symptom during the menopausal transition, caused by a complex interplay of hormonal changes, neurovascular dysregulation, and, possibly, inflammation. The decrease in estrogen levels disrupts the hypothalamus’s ability to regulate body temperature, leading to exaggerated thermoregulatory responses, such as vasodilation and sweating.[13] These episodes can vary in severity, duration, and frequency, affecting women differently based on various factors, including genetics, ethnicity, and lifestyle.[14][15] While estrogen deficiency remains the primary cause, the role of neurotransmitters like serotonin and norepinephrine, along with inflammatory markers such as TNF-α and IL-8, is increasingly recognized in the pathophysiology of hot flashes.[16] The impact of these symptoms on a woman’s quality of life is profound, leading to sleep disturbances, anxiety, and long-term health risks, which underscores the importance of comprehensive management strategies that address both the physiological and psychological aspects of menopause.[17]
Metallomic Signature
Exposure to environmental contaminants, including heavy metals like cadmium, mercury, and lead, has been shown to influence hormonal regulation and may exacerbate menopausal symptoms, particularly hot flashes.[18] Studies have indicated that these metals, which are ubiquitous in the environment, can disrupt the hypothalamic-pituitary-ovarian axis, potentially leading to earlier onset menopause and more severe vasomotor symptoms. For example, higher urinary levels of lead and mercury have been associated with lower estradiol (E2) levels and higher follicle-stimulating hormone (FSH) levels in midlife women. Such hormonal alterations suggest that exposure to heavy metals may accelerate ovarian aging, contributing to more pronounced hot flashes during the menopausal transition.[19] Moreover, smoking, both active and passive,, has been identified as a major contributor to heavy metal exposure, particularly cadmium, which is found in tobacco smoke. Smokers are more likely to have elevated levels of cadmium, and this metal has been linked to changes in reproductive hormones, including lower E2 and altered FSH levels.[20] Interestingly, even non-smokers exposed to secondhand smoke show increased metal exposure and worsened vasomotor symptoms, highlighting the broad impact of environmental contaminants on menopausal health. The interplay between smoking, metal exposure, and menopausal symptoms underscores the need for a more integrated approach to managing these factors, especially as women undergo menopause.
Metabolomic Signatures
Phthalates have been implicated in influencing menopausal symptoms, including hot flashes. Studies have shown that exposure to phthalate metabolites, particularly those from personal care products, correlates with an increased risk of experiencing hot flashes in midlife women. Phthalates, such as diethyl phthalate (DEP) and di(2-ethylhexyl) phthalate (DEHP), are metabolized into various compounds that have been associated with hormone disruption, particularly influencing estradiol levels.[21] This hormone imbalance is a known driver of hot flashes, as the drop in estradiol during menopause is thought to contribute to the vasomotor symptoms of the condition. In a study of midlife women, higher urinary concentrations of phthalate metabolites, particularly those associated with plasticizers, were found to increase the odds of experiencing hot flashes.[22] The associations between phthalate metabolites and hot flashes were particularly strong in women with lower body mass indexe (BMI) and those with depressive symptoms. These findings suggest that phthalate exposure, through its impact on reproductive hormones, might exacerbate menopausal symptoms, especially in susceptible populations.[23] The mechanism by which phthalates contribute to hot flashes likely involves hormonal disruptions, where phthalates, particularly DEHP and its metabolites, decrease estradiol and progesterone levels.
Microbiome Signature: Menopausal Hot Flashes
Interventions
In recent years, there has been increasing interest in microbiome-targeted interventions, as gut health has been shown to influence hormonal regulation and inflammation, which may contribute to the severity of hot flashes. Dietary changes, probiotics, and other microbiome-modulating interventions have been studied for their potential to reduce menopausal symptoms, with some promising results. For example, low-fat plant-based diets rich in phytoestrogens, particularly soybeans, have been associated with improvements in hot flash frequency, potentially through modulation of gut microbiota. Emerging evidence suggests that manipulating gut bacteria involved in estrogen metabolism, like Prevotella and Clostridium, can influence the severity of hot flashes. This area of research highlights the need for a holistic approach to managing menopause, incorporating both hormonal and non-hormonal therapies that target the gut-brain axis and hormonal pathways.
| Interventions | Mechanisms of Action | MBTI Status |
|---|---|---|
| Phytoestrogens (e.g., Salvia Officinalis) | Probiotics modulate gut microbiota composition, influencing estrogen metabolism and inflammatory pathways.[24] Potentially reduces hot flash frequency by regulating gut health and improving hormonal balance.[25] | Promising Candidate |
| Probiotics | Probiotics modulates gut microbiota composition, influencing estrogen metabolism and inflammatory pathways.[26] Potentially reduces hot flash frequency by regulating gut health and improving hormonal balance.[27] | Experimental |
| Synbiotics | Modulates the gut-brain axis, influencing mood and vasomotor symptoms through a balance of beneficial bacteria and dietary fibers, potentially reducing hot flash frequency.[28] | Experimental |
| SSRIs | SSRIs modulates serotonin and norepinephrine reuptake, potentially reducing hot flash frequency and severity through mood regulation and thermoregulatory effects.[29] | Validated |
| Low-fat Vegan Diet | Reduces dietary advanced glycation end-products (AGEs), which are associated with inflammation and oxidative stress. Modulation of AGEs may alleviate hot flashes.[30][31] | Experimental |
| Herbal Tea (e.g., Lavender, Humulus Lupulus) | Utilizes compounds like phytoestrogens and antioxidants to modulate hormonal and thermoregulatory pathways, potentially reducing hot flash intensity.[32][33] | Promising Candidate |
| Metformin | Metformin reduces insulin resistance, stabilizes blood glucose levels, and may alleviate hot flashes by preventing glucose fluctuations, which can trigger thermoregulatory responses.[34] | Promising Candidate |
| Dietary Change (Low-fat, plant-based) | Modulates gut microbiota, enhancing estrogen metabolism and potentially reducing hot flash frequency by promoting the growth of gut bacteria that produce phytoestrogens and other metabolites involved in estrogenic activity.[35] | Under Investigation |
FAQs
How does the microbiome influence menopausal hot flashes?
How does the microbiome influence menopausal hot flashes?
The gut microbiome, which consists of trillions of bacteria residing in the digestive tract, plays a crucial role in regulating estrogen metabolism and influencing systemic inflammation—both of which are important factors in the onset and severity of menopausal hot flashes. Certain bacteria in the gut, collectively referred to as the estrobolome, are involved in the biotransformation of estrogens into metabolites that can either activate or deactivate estrogen receptors. When the microbiome is in balance, it helps maintain estrogen levels, which can reduce the frequency and intensity of hot flashes. However, when the gut microbiota becomes imbalanced, a condition known as dysbiosis, it can disrupt estrogen metabolism and increase inflammation, which may worsen hot flashes. Some studies have shown that diets high in fiber, polyphenols, and fermented foods, which promote the growth of beneficial gut bacteria, can alleviate menopausal symptoms, including hot flashes. Modulating the gut microbiome through probiotics, prebiotics, and dietary interventions holds promise as a non-hormonal approach to managing hot flashes, especially for women who cannot or choose not to undergo hormone replacement therapy.
How can blood glucose management help with hot flashes, and is there a link between insulin resistance and hot flash severity?
How can blood glucose management help with hot flashes, and is there a link between insulin resistance and hot flash severity?
Blood glucose management is increasingly recognized as a key factor in reducing hot flash severity during menopause. Fluctuations in blood glucose levels, particularly when blood sugar drops between meals, can trigger hot flashes in susceptible women. This is due to the impaired glucose transport across the blood-brain barrier (BBB), which becomes more pronounced during menopause due to estrogen decline. A stable blood glucose level helps maintain proper brain function and thermoregulation, reducing the likelihood of hot flashes. Studies have shown that women who manage their blood glucose levels through regular meals and a balanced diet experience fewer hot flashes. Additionally, there is evidence that insulin resistance, which often occurs during menopause due to metabolic changes, can exacerbate hot flash severity. Managing blood glucose levels through dietary changes, physical activity, and, if necessary, medication, can help alleviate hot flashes by preventing blood sugar dips and reducing insulin resistance. This makes blood glucose regulation a crucial part of managing menopausal symptoms effectively.
What are the long-term health effects of hot flashes beyond the discomfort they cause?
What are the long-term health effects of hot flashes beyond the discomfort they cause?
Hot flashes are more than just an uncomfortable symptom of menopause; they can have lasting effects on a woman’s overall health. Chronic hot flashes have been associated with an increased risk of cardiovascular disease (CVD) due to the vasomotor instability they cause, such as rapid fluctuations in blood pressure and heart rate. The frequent dilation and constriction of blood vessels can put extra strain on the cardiovascular system, leading to long-term health issues. Additionally, the sleep disturbances caused by night sweats and hot flashes can lead to chronic fatigue, cognitive impairment, and mood disorders like anxiety and depression. Over time, these compounded effects can significantly lower a woman’s quality of life. Studies have also linked severe and frequent hot flashes to higher rates of osteoporosis and bone fractures. This is partly because estrogen plays a protective role in maintaining bone density, and its decline during menopause, coupled with the stress of hot flashes, may accelerate bone loss. Managing hot flashes through lifestyle modifications, dietary interventions, or non-hormonal therapies can help reduce these risks and improve long-term health outcomes.
Research Feed
A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome
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The effect of dietary intake on hot flashes in menopausal women
December 16, 2015
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Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
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The effect of herbal tea capsule on menopause hot flashes
Menopause •
Menopause
Did You Know?
Osteoporosis affects one in three women over 50. Estrogen decline during menopause accelerates bone loss, making weight-bearing exercises, calcium, and vitamin D essential for maintaining bone health. Early intervention can reduce fracture risk, and the gut microbiome may play a role in improving bone density.
Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
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Microbiome Insiders can read two study summaries for any topic on Microbiome.
Menopause hot flashes and molecular mechanisms modulated by food-derived nutrients
February 26, 2024
/
Menopause •
Menopause
Did You Know?
Osteoporosis affects one in three women over 50. Estrogen decline during menopause accelerates bone loss, making weight-bearing exercises, calcium, and vitamin D essential for maintaining bone health. Early intervention can reduce fracture risk, and the gut microbiome may play a role in improving bone density.
Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
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Microbiome Insiders can read two study summaries for any topic on Microbiome.
Dietary advanced glycation end-products and postmenopausal hot flashes
March 24, 2023
/
Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
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Diet quality, body weight, and postmenopausal hot flashes: a secondary analysis of a randomized clinical trial
December 23, 2024
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Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
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User Outcomes for an App-Delivered Hypnosis Intervention for Menopausal Hot Flashes: Retrospective Analysis.
July 3, 2024
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Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
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Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes
April 3, 2017
/
Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
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SSRIs for hot flashes: a systematic review and meta-analysis of randomized trials.
July 26, 2013
/
Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
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The Effect of Salvia Officinalis on Hot Flashes in Postmenopausal Women
July 1, 2023
/
Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
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Exposure to heavy metals and hormone levels in midlife women
January 15, 2023
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Metals •
Metals
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Proin ut laoreet tortor. Donec euismod fermentum pharetra. Nullam at tristique enim. In sit amet molestie
Menopause •
Menopause
Did You Know?
Osteoporosis affects one in three women over 50. Estrogen decline during menopause accelerates bone loss, making weight-bearing exercises, calcium, and vitamin D essential for maintaining bone health. Early intervention can reduce fracture risk, and the gut microbiome may play a role in improving bone density.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
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The Effects of Environmental Contaminant Exposure on Reproductive Aging and the Menopause Transition
February 1, 2022
/
Menopause •
Menopause
Did You Know?
Osteoporosis affects one in three women over 50. Estrogen decline during menopause accelerates bone loss, making weight-bearing exercises, calcium, and vitamin D essential for maintaining bone health. Early intervention can reduce fracture risk, and the gut microbiome may play a role in improving bone density.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
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Urinary phthalate metabolite concentrations and hot flashes in women from an urban convenience sample of midlife women
March 17, 2021
/
Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
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Phthalate metabolite levels and menopausal hot flashes in midlife women
February 8, 2016
/
Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
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Severe hot flashes are associated with chronic insomnia
June 25, 2006
/
Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
Create a free account to unlock this study summary.
Microbiome Insiders can read two study summaries for any topic on Microbiome.
Circulating interleukin-8 and tumor necrosis factor-α are associated with hot flashes in healthy postmenopausal women
August 28, 2017
/
Menopause •
Menopause
Did You Know?
Osteoporosis affects one in three women over 50. Estrogen decline during menopause accelerates bone loss, making weight-bearing exercises, calcium, and vitamin D essential for maintaining bone health. Early intervention can reduce fracture risk, and the gut microbiome may play a role in improving bone density.
Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
Create a free account to unlock this study summary.
Microbiome Insiders can read two study summaries for any topic on Microbiome.
Prevalence of hot flushes and night sweats around the world: a systematic review
July 3, 2009
/
Menopause •
Menopause
Did You Know?
Osteoporosis affects one in three women over 50. Estrogen decline during menopause accelerates bone loss, making weight-bearing exercises, calcium, and vitamin D essential for maintaining bone health. Early intervention can reduce fracture risk, and the gut microbiome may play a role in improving bone density.
Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
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What’s in a name: are menopausal “hot flashes” a symptom of menopause or a manifestation of neurovascular dysregulation?
June 1, 2019
/
Menopause •
Menopause
Did You Know?
Osteoporosis affects one in three women over 50. Estrogen decline during menopause accelerates bone loss, making weight-bearing exercises, calcium, and vitamin D essential for maintaining bone health. Early intervention can reduce fracture risk, and the gut microbiome may play a role in improving bone density.
Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
Create a free account to unlock this study summary.
Microbiome Insiders can read two study summaries for any topic on Microbiome.
Menopausal hot flashes: mechanisms, endocrinology, treatment
October 20, 2015
/
Menopause •
Menopause
Did You Know?
Osteoporosis affects one in three women over 50. Estrogen decline during menopause accelerates bone loss, making weight-bearing exercises, calcium, and vitamin D essential for maintaining bone health. Early intervention can reduce fracture risk, and the gut microbiome may play a role in improving bone density.
Menopausal Hot Flashes •
Menopausal Hot Flashes
Did you know?
Hot flashes might be triggered by something as simple as a cup of coffee? Yes, that morning cup could be fueling more than just your energy. Caffeine is a well-known trigger for hot flashes because it can elevate your heart rate and increase blood flow, both of which contribute to the intense heat sensation.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
Create a free account to unlock this study summary.
Microbiome Insiders can read two study summaries for any topic on Microbiome.
Menopausal Hot Flashes: A Review of Physiology and Biosociocultural Perspective on Methods of Assessment
May 26, 2010
/
Menopause •
Menopause
Did You Know?
Osteoporosis affects one in three women over 50. Estrogen decline during menopause accelerates bone loss, making weight-bearing exercises, calcium, and vitamin D essential for maintaining bone health. Early intervention can reduce fracture risk, and the gut microbiome may play a role in improving bone density.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
Create a free account to unlock this study summary.
Microbiome Insiders can read two study summaries for any topic on Microbiome.
Menopausal Hot Flashes: A Concise Review
Menopause •
Menopause
Did You Know?
Osteoporosis affects one in three women over 50. Estrogen decline during menopause accelerates bone loss, making weight-bearing exercises, calcium, and vitamin D essential for maintaining bone health. Early intervention can reduce fracture risk, and the gut microbiome may play a role in improving bone density.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
Create a free account to unlock this study summary.
Microbiome Insiders can read two study summaries for any topic on Microbiome.
What’s in a name: are menopausal ‘hot flashes’ a symptom of menopause or a manifestation of neurovascular dysregulation?
June 1, 2018
/
Menopause •
Menopause
Did You Know?
Osteoporosis affects one in three women over 50. Estrogen decline during menopause accelerates bone loss, making weight-bearing exercises, calcium, and vitamin D essential for maintaining bone health. Early intervention can reduce fracture risk, and the gut microbiome may play a role in improving bone density.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
Create a free account to unlock this study summary.
Microbiome Insiders can read two study summaries for any topic on Microbiome.
The relationship between menopausal syndrome and gut microbes
November 8, 2022
/
Menopause •
Menopause
Did You Know?
Osteoporosis affects one in three women over 50. Estrogen decline during menopause accelerates bone loss, making weight-bearing exercises, calcium, and vitamin D essential for maintaining bone health. Early intervention can reduce fracture risk, and the gut microbiome may play a role in improving bone density.
Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.
Create a free account to unlock this study summary.
Microbiome Insiders can read two study summaries for any topic on Microbiome.
Update History
2025-07-14 15:02:25
Menopausal Hot Flashes majorpublished
Probiotics
Probiotics are live microorganisms that offer significant health benefits when administered in adequate amounts. They primarily work by modulating the gut microbiome, supporting a balanced microbial ecosystem. Probiotics have been shown to improve gut health, modulate immune responses, and even influence metabolic and mental health disorders. With growing evidence supporting their therapeutic potential, probiotics are increasingly recognized for their role in treating conditions like irritable bowel syndrome (IBS), antibiotic-associated diarrhea (AAD), and even mental health conditions like depression and anxiety through their impact on the gut-brain axis.
Metformin
Metformin is a synthetic derivative of guanidine derived from the guanidine alkaloid of the plant Galega officinalis L. with significant hypoglycemic effects. It is a first-line antihyperglycemic agent due to its efficacy, low cost, and favorable safety profile.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopause
Menopause impacts many aspects of health, including the gut microbiome, weight management, and hormone balance. Diet, probiotics, intermittent fasting, and HRT offer effective management strategies.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopause
Menopause impacts many aspects of health, including the gut microbiome, weight management, and hormone balance. Diet, probiotics, intermittent fasting, and HRT offer effective management strategies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopause
Menopause impacts many aspects of health, including the gut microbiome, weight management, and hormone balance. Diet, probiotics, intermittent fasting, and HRT offer effective management strategies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopause
Menopause impacts many aspects of health, including the gut microbiome, weight management, and hormone balance. Diet, probiotics, intermittent fasting, and HRT offer effective management strategies.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopause
Menopause impacts many aspects of health, including the gut microbiome, weight management, and hormone balance. Diet, probiotics, intermittent fasting, and HRT offer effective management strategies.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopause
Menopause impacts many aspects of health, including the gut microbiome, weight management, and hormone balance. Diet, probiotics, intermittent fasting, and HRT offer effective management strategies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopause
Menopause impacts many aspects of health, including the gut microbiome, weight management, and hormone balance. Diet, probiotics, intermittent fasting, and HRT offer effective management strategies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopause
Menopause impacts many aspects of health, including the gut microbiome, weight management, and hormone balance. Diet, probiotics, intermittent fasting, and HRT offer effective management strategies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopause
Menopause impacts many aspects of health, including the gut microbiome, weight management, and hormone balance. Diet, probiotics, intermittent fasting, and HRT offer effective management strategies.
Menopausal Hot Flashes
Menopausal hot flashes are one of the most common and disruptive symptoms that women experience during the transition to menopause. Characterized by sudden sensations of heat, sweating, and flushing, hot flashes can significantly affect a woman’s quality of life, causing sleep disturbances, mood swings, and even long-term health consequences. Understanding the complex mechanisms behind hot flashes, as well as the role of microbiome-targeted therapies, offers new avenues for improving menopausal health.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopause
Menopause impacts many aspects of health, including the gut microbiome, weight management, and hormone balance. Diet, probiotics, intermittent fasting, and HRT offer effective management strategies.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopause
Menopause impacts many aspects of health, including the gut microbiome, weight management, and hormone balance. Diet, probiotics, intermittent fasting, and HRT offer effective management strategies.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopause
Menopause impacts many aspects of health, including the gut microbiome, weight management, and hormone balance. Diet, probiotics, intermittent fasting, and HRT offer effective management strategies.
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
Menopause
Menopause impacts many aspects of health, including the gut microbiome, weight management, and hormone balance. Diet, probiotics, intermittent fasting, and HRT offer effective management strategies.
References
- Menopausal hot flashes: A concise review.. Bansal R, Aggarwal N.. (J Mid-life Health. 2019;10(1):6-13.)
- Menopausal hot flashes: Mechanisms, endocrinology, treatment.. Freedman, R. R. (2014).. (Journal of Steroid Biochemistry and Molecular Biology, 142, 115–120.)
- Menopausal hot flashes: A concise review.. Bansal R, Aggarwal N.. (J Mid-life Health. 2019;10(1):6-13.)
- Severe hot flashes are associated with chronic insomnia in midlife women.. Ohayon, M. M. (2006).. (Archives of Internal Medicine, 166(12), 1262-1268.)
- Menopausal hot flashes: A review of physiology and biosociocultural perspective on methods of assessment. Kronenberg, F. (2010).. (The Journal of Nutrition, 140(7), 1380S–1385S.)
- What's in a name: are menopausal “hot flashes” a symptom of menopause or a manifestation of neurovascular dysregulation?. Miller, V. M., Kling, J. M., Files, J. A., Joyner, M. J., Kapoor, E., Moyer, A. M., Rocca, W. A., & Faubion, S. S. (2018).. (Menopause, 25(6), 700–703.)
- Circulating interleukin-8 and tumor necrosis factor-α are associated with hot flashes in healthy postmenopausal women.. Huang, W.-Y., Hsin, I.-L., Chen, D.-R., Chang, C.-C., Kor, C.-T., Chen, T.-Y., & Wu, H.-M. (2017).. (PLOS ONE, 12(8), e0184011.)
- Menopausal hot flashes: A review of physiology and biosociocultural perspective on methods of assessment. Kronenberg, F. (2010).. (The Journal of Nutrition, 140(7), 1380S–1385S.)
- Menopausal hot flashes: Mechanisms, endocrinology, treatment.. Freedman, R. R. (2014).. (Journal of Steroid Biochemistry and Molecular Biology, 142, 115–120.)
- Circulating interleukin-8 and tumor necrosis factor-α are associated with hot flashes in healthy postmenopausal women.. Huang, W.-Y., Hsin, I.-L., Chen, D.-R., Chang, C.-C., Kor, C.-T., Chen, T.-Y., & Wu, H.-M. (2017).. (PLOS ONE, 12(8), e0184011.)
- Menopausal hot flashes: A review of physiology and biosociocultural perspective on methods of assessment. Kronenberg, F. (2010).. (The Journal of Nutrition, 140(7), 1380S–1385S.)
- Circulating interleukin-8 and tumor necrosis factor-α are associated with hot flashes in healthy postmenopausal women.. Huang, W.-Y., Hsin, I.-L., Chen, D.-R., Chang, C.-C., Kor, C.-T., Chen, T.-Y., & Wu, H.-M. (2017).. (PLOS ONE, 12(8), e0184011.)
- Menopausal hot flashes: Mechanisms, endocrinology, treatment.. Freedman, R. R. (2014).. (Journal of Steroid Biochemistry and Molecular Biology, 142, 115–120.)
- What's in a name: are menopausal “hot flashes” a symptom of menopause or a manifestation of neurovascular dysregulation?. Miller, V. M., Kling, J. M., Files, J. A., Joyner, M. J., Kapoor, E., Moyer, A. M., Rocca, W. A., & Faubion, S. S. (2018).. (Menopause, 25(6), 700–703.)
- Prevalence of hot flushes and night sweats around the world: A systematic review.. Freeman, E. W., & Sherif, K. (2007).. (Climacteric, 10(3), 197-214.)
- Circulating interleukin-8 and tumor necrosis factor-α are associated with hot flashes in healthy postmenopausal women.. Huang, W.-Y., Hsin, I.-L., Chen, D.-R., Chang, C.-C., Kor, C.-T., Chen, T.-Y., & Wu, H.-M. (2017).. (PLOS ONE, 12(8), e0184011.)
- Menopausal hot flashes: A concise review.. Bansal R, Aggarwal N.. (J Mid-life Health. 2019;10(1):6-13.)
- Exposure to heavy metals and hormone levels in midlife women: The Study of Women’s Health Across the Nation (SWAN).. Wang X, Ding N, Harlow SD, Randolph JF Jr, Mukherjee B, Gold EB, Park SK.. (Environ Pollut. 2023 Jan 15;317:120740.)
- Cadmium, Lead, and Mercury in Relation to Reproductive Hormones and Anovulation in Premenopausal Women.. Pollack, A. Z., Schisterman, E. F., Goldman, L. R., Mumford, S. L., Albert, P. S., Jones, R. L., & Wactawski-Wende, J. (2011).. (Environmental Health Perspectives, 119(8), 1156.)
- The effects of environmental contaminant exposure on reproductive aging and the menopause transition.. Neff AM, Laws MJ, Warner GR, Flaws JA.. (Curr Environ Health Rep. 2022;9(1):53–79.)
- Phthalate metabolite levels and menopausal hot flashes in midlife women.. Ziv-Gal, A., Gallicchio, L., Chiang, C., Thera, S. N., Miller, S. R., Zacur, H. A., Dills, R. L., & Flaws, J. A. (2016).. (Reproductive Toxicology, 60, 76–81.)
- Phthalate metabolite levels and menopausal hot flashes in midlife women.. Ziv-Gal, A., Gallicchio, L., Chiang, C., Thera, S. N., Miller, S. R., Zacur, H. A., Dills, R. L., & Flaws, J. A. (2016).. (Reproductive Toxicology, 60, 76–81.)
- Urinary phthalate metabolite concentrations and hot flashes in women from an urban convenience sample of midlife women.. Warner, G. R., Pacyga, D. C., Strakovsky, R. S., Smith, R., James-Todd, T., Williams, P. L., Hauser, R., Meling, D. D., Li, Z., & Flaws, J. A. (2021).. (Environmental Research, 197, 110891.)
- Impact of Probiotics and Prebiotics on Gut Microbiome and Hormonal Regulation.. Basnet, J., Eissa, M. A., Yanes Cardozo, L. L., Romero, D. G., & Rezq, S. (2024).. (Gastrointestinal Disorders, 6(4), 801-815.)
- Complement Ther Med. 2023;79:103002.. Kahleova H, Holtz DN, Strom N, et al.. (A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome.)
- Impact of Probiotics and Prebiotics on Gut Microbiome and Hormonal Regulation.. Basnet, J., Eissa, M. A., Yanes Cardozo, L. L., Romero, D. G., & Rezq, S. (2024).. (Gastrointestinal Disorders, 6(4), 801-815.)
- Complement Ther Med. 2023;79:103002.. Kahleova H, Holtz DN, Strom N, et al.. (A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome.)
- Impact of Probiotics and Prebiotics on Gut Microbiome and Hormonal Regulation.. Basnet, J., Eissa, M. A., Yanes Cardozo, L. L., Romero, D. G., & Rezq, S. (2024).. (Gastrointestinal Disorders, 6(4), 801-815.)
- SSRIs for hot flashes: a systematic review and meta-analysis of randomized trials.. Shams T, Firwana B, Habib F, Alshahrani A, Alnouh B, Murad MH, Ferwana M.. (J Gen Intern Med. 2014 Jan;29(1):204-13.)
- Dietary advanced glycation end-products and postmenopausal hot flashes: A post-hoc analysis of a 12-week randomized clinical trial.. Kahleova, H., Znayenko-Miller, T., Uribarri, J., Schmidt, N., Kolipaka, S., Hata, E., Holtz, D. N., Sutton, M., Holubkov, R., & Barnard, N. D. (2023).. (Maturitas, 172, 32-38.)
- Diet quality, body weight, and postmenopausal hot flashes: A secondary analysis of a randomized clinical trial.. Brennan, H., Znayenko-Miller, T., Sutton, M., Holubkov, R., & Kahleova, H. (2024).. (BMC Women's Health, 24(620).)
- Protocol for systematic review and meta-analysis: Hop (Humulus lupulus L.) for menopausal vasomotor symptoms.. Abdi, F., Kazemi, F., Tehrani, F. R., & Roozbeh, N. (2016).. (BMJ Open, 6(4), e010734.)
- Effect of Lavender on Sleep, Sexual Desire, Vasomotor, Psychological and Physical Symptom among Menopausal and Elderly Women: A Systematic Review.. Roozbeh, N., Ghazanfarpour, M., Khadivzadeh, T., Kargarfard, L., Dizavandi, F. R., & Shariati, K. (2019).. (Journal of Menopausal Medicine, 25(2), 88.)
- Hot flashes and fatigue relieved by metformin.. Maudar V, Winters SJ, Villafuerte BC.. (Endocr Pract. 2009 Jan-Feb;15(1):30-4.)
- Complement Ther Med. 2023;79:103002.. Kahleova H, Holtz DN, Strom N, et al.. (A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome.)
Bansal R, Aggarwal N.
Menopausal hot flashes: A concise review.J Mid-life Health. 2019;10(1):6-13.
Read ReviewFreedman, R. R. (2014).
Menopausal hot flashes: Mechanisms, endocrinology, treatment.Journal of Steroid Biochemistry and Molecular Biology, 142, 115–120.
Read ReviewBansal R, Aggarwal N.
Menopausal hot flashes: A concise review.J Mid-life Health. 2019;10(1):6-13.
Read ReviewOhayon, M. M. (2006).
Severe hot flashes are associated with chronic insomnia in midlife women.Archives of Internal Medicine, 166(12), 1262-1268.
Read ReviewKronenberg, F. (2010).
Menopausal hot flashes: A review of physiology and biosociocultural perspective on methods of assessmentThe Journal of Nutrition, 140(7), 1380S–1385S.
Read ReviewMiller, V. M., Kling, J. M., Files, J. A., Joyner, M. J., Kapoor, E., Moyer, A. M., Rocca, W. A., & Faubion, S. S. (2018).
What's in a name: are menopausal “hot flashes” a symptom of menopause or a manifestation of neurovascular dysregulation?Menopause, 25(6), 700–703.
Read ReviewHuang, W.-Y., Hsin, I.-L., Chen, D.-R., Chang, C.-C., Kor, C.-T., Chen, T.-Y., & Wu, H.-M. (2017).
Circulating interleukin-8 and tumor necrosis factor-α are associated with hot flashes in healthy postmenopausal women.PLOS ONE, 12(8), e0184011.
Read ReviewKronenberg, F. (2010).
Menopausal hot flashes: A review of physiology and biosociocultural perspective on methods of assessmentThe Journal of Nutrition, 140(7), 1380S–1385S.
Read ReviewFreedman, R. R. (2014).
Menopausal hot flashes: Mechanisms, endocrinology, treatment.Journal of Steroid Biochemistry and Molecular Biology, 142, 115–120.
Read ReviewHuang, W.-Y., Hsin, I.-L., Chen, D.-R., Chang, C.-C., Kor, C.-T., Chen, T.-Y., & Wu, H.-M. (2017).
Circulating interleukin-8 and tumor necrosis factor-α are associated with hot flashes in healthy postmenopausal women.PLOS ONE, 12(8), e0184011.
Read ReviewKronenberg, F. (2010).
Menopausal hot flashes: A review of physiology and biosociocultural perspective on methods of assessmentThe Journal of Nutrition, 140(7), 1380S–1385S.
Read ReviewHuang, W.-Y., Hsin, I.-L., Chen, D.-R., Chang, C.-C., Kor, C.-T., Chen, T.-Y., & Wu, H.-M. (2017).
Circulating interleukin-8 and tumor necrosis factor-α are associated with hot flashes in healthy postmenopausal women.PLOS ONE, 12(8), e0184011.
Read ReviewFreedman, R. R. (2014).
Menopausal hot flashes: Mechanisms, endocrinology, treatment.Journal of Steroid Biochemistry and Molecular Biology, 142, 115–120.
Read ReviewMiller, V. M., Kling, J. M., Files, J. A., Joyner, M. J., Kapoor, E., Moyer, A. M., Rocca, W. A., & Faubion, S. S. (2018).
What's in a name: are menopausal “hot flashes” a symptom of menopause or a manifestation of neurovascular dysregulation?Menopause, 25(6), 700–703.
Read ReviewFreeman, E. W., & Sherif, K. (2007).
Prevalence of hot flushes and night sweats around the world: A systematic review.Climacteric, 10(3), 197-214.
Read ReviewHuang, W.-Y., Hsin, I.-L., Chen, D.-R., Chang, C.-C., Kor, C.-T., Chen, T.-Y., & Wu, H.-M. (2017).
Circulating interleukin-8 and tumor necrosis factor-α are associated with hot flashes in healthy postmenopausal women.PLOS ONE, 12(8), e0184011.
Read ReviewBansal R, Aggarwal N.
Menopausal hot flashes: A concise review.J Mid-life Health. 2019;10(1):6-13.
Read ReviewWang X, Ding N, Harlow SD, Randolph JF Jr, Mukherjee B, Gold EB, Park SK.
Exposure to heavy metals and hormone levels in midlife women: The Study of Women’s Health Across the Nation (SWAN).Environ Pollut. 2023 Jan 15;317:120740.
Read ReviewPollack, A. Z., Schisterman, E. F., Goldman, L. R., Mumford, S. L., Albert, P. S., Jones, R. L., & Wactawski-Wende, J. (2011).
Cadmium, Lead, and Mercury in Relation to Reproductive Hormones and Anovulation in Premenopausal Women.Environmental Health Perspectives, 119(8), 1156.
Neff AM, Laws MJ, Warner GR, Flaws JA.
The effects of environmental contaminant exposure on reproductive aging and the menopause transition.Curr Environ Health Rep. 2022;9(1):53–79.
Read ReviewZiv-Gal, A., Gallicchio, L., Chiang, C., Thera, S. N., Miller, S. R., Zacur, H. A., Dills, R. L., & Flaws, J. A. (2016).
Phthalate metabolite levels and menopausal hot flashes in midlife women.Reproductive Toxicology, 60, 76–81.
Read ReviewZiv-Gal, A., Gallicchio, L., Chiang, C., Thera, S. N., Miller, S. R., Zacur, H. A., Dills, R. L., & Flaws, J. A. (2016).
Phthalate metabolite levels and menopausal hot flashes in midlife women.Reproductive Toxicology, 60, 76–81.
Read ReviewWarner, G. R., Pacyga, D. C., Strakovsky, R. S., Smith, R., James-Todd, T., Williams, P. L., Hauser, R., Meling, D. D., Li, Z., & Flaws, J. A. (2021).
Urinary phthalate metabolite concentrations and hot flashes in women from an urban convenience sample of midlife women.Environmental Research, 197, 110891.
Read ReviewBasnet, J., Eissa, M. A., Yanes Cardozo, L. L., Romero, D. G., & Rezq, S. (2024).
Impact of Probiotics and Prebiotics on Gut Microbiome and Hormonal Regulation.Gastrointestinal Disorders, 6(4), 801-815.
Kahleova H, Holtz DN, Strom N, et al.
Complement Ther Med. 2023;79:103002.A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome.
Read ReviewBasnet, J., Eissa, M. A., Yanes Cardozo, L. L., Romero, D. G., & Rezq, S. (2024).
Impact of Probiotics and Prebiotics on Gut Microbiome and Hormonal Regulation.Gastrointestinal Disorders, 6(4), 801-815.
Kahleova H, Holtz DN, Strom N, et al.
Complement Ther Med. 2023;79:103002.A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome.
Read ReviewBasnet, J., Eissa, M. A., Yanes Cardozo, L. L., Romero, D. G., & Rezq, S. (2024).
Impact of Probiotics and Prebiotics on Gut Microbiome and Hormonal Regulation.Gastrointestinal Disorders, 6(4), 801-815.
Shams T, Firwana B, Habib F, Alshahrani A, Alnouh B, Murad MH, Ferwana M.
SSRIs for hot flashes: a systematic review and meta-analysis of randomized trials.J Gen Intern Med. 2014 Jan;29(1):204-13.
Read ReviewKahleova, H., Znayenko-Miller, T., Uribarri, J., Schmidt, N., Kolipaka, S., Hata, E., Holtz, D. N., Sutton, M., Holubkov, R., & Barnard, N. D. (2023).
Dietary advanced glycation end-products and postmenopausal hot flashes: A post-hoc analysis of a 12-week randomized clinical trial.Maturitas, 172, 32-38.
Read ReviewBrennan, H., Znayenko-Miller, T., Sutton, M., Holubkov, R., & Kahleova, H. (2024).
Diet quality, body weight, and postmenopausal hot flashes: A secondary analysis of a randomized clinical trial.BMC Women's Health, 24(620).
Read ReviewAbdi, F., Kazemi, F., Tehrani, F. R., & Roozbeh, N. (2016).
Protocol for systematic review and meta-analysis: Hop (Humulus lupulus L.) for menopausal vasomotor symptoms.BMJ Open, 6(4), e010734.
Roozbeh, N., Ghazanfarpour, M., Khadivzadeh, T., Kargarfard, L., Dizavandi, F. R., & Shariati, K. (2019).
Effect of Lavender on Sleep, Sexual Desire, Vasomotor, Psychological and Physical Symptom among Menopausal and Elderly Women: A Systematic Review.Journal of Menopausal Medicine, 25(2), 88.
Maudar V, Winters SJ, Villafuerte BC.
Hot flashes and fatigue relieved by metformin.Endocr Pract. 2009 Jan-Feb;15(1):30-4.
Kahleova H, Holtz DN, Strom N, et al.
Complement Ther Med. 2023;79:103002.A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome.
Read Review