Impact of nutritional diet therapy on premenstrual syndrome Original paper
Researched by:
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Divine Aleru
ID
Divine Aleru
I am a biochemist with a deep curiosity for the human microbiome and how it shapes human health, and I enjoy making microbiome science more accessible through research and writing. With 2 years experience in microbiome research, I have curated microbiome studies, analyzed microbial signatures, and now focus on interventions as a Microbiome Signatures and Interventions Research Coordinator.
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Women’s Health
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
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Premenstrual Dysphoric Disorder (PMDD)
Premenstrual Dysphoric Disorder (PMDD)
Premenstrual Dysphoric Disorder (PMDD) is a severe mood disorder linked to hormonal and neurochemical changes. Emerging research highlights the gut microbiome’s role in symptom modulation, opening new avenues for microbiome-targeted treatments alongside traditional therapies.
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Premenstrual Syndrome (PMS)
Premenstrual Syndrome (PMS)
Premenstrual Syndrome (PMS) involves physical and emotional symptoms linked to hormonal fluctuations. Recent research highlights the role of heavy metals and gut microbiome imbalances in worsening these symptoms. Lifestyle changes, microbiome-targeted therapies, and toxin reduction show promise in effective PMS management.
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Divine Aleru
Researched by:
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Divine Aleru
ID
Divine Aleru
Microbiome Signatures identifies and validates condition-specific microbiome shifts and interventions to accelerate clinical translation. Our multidisciplinary team supports clinicians, researchers, and innovators in turning microbiome science into actionable medicine.
Divine Aleru
What was reviewed?
This paper conducted a comprehensive review of current research on the effects of dietary and nutritional therapies on premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) symptoms. The authors analyzed data from various studies accessed through major databases like PubMed, ScienceDirect, and Scopus, focusing on dietary patterns, macro- and micronutrients, supplements, and their relationship to PMS symptom severity and management.
Who was reviewed?
The review synthesized findings from multiple clinical and observational studies involving women of reproductive age experiencing PMS, encompassing diverse populations and dietary behaviors. The included studies examined correlations between specific nutrients, food groups, supplements, and premenstrual symptom patterns.
What were the most important findings?
The review emphasized that while diet plays an important role in modulating PMS symptoms, the scientific evidence remains limited and inconsistent, especially regarding macronutrient intake—no strong correlations were found between protein, fat, carbohydrates, or fiber consumption and PMS symptoms. However, micronutrients such as calcium, magnesium, vitamin D, and B vitamins showed potential benefits in symptom reduction. Specifically, calcium and vitamin D supplementation were linked to decreased PMS symptom severity and improved quality of life, although definitive clinical recommendations require further trials. The role of vitamin B6 and broad-spectrum micronutrient supplementation was also noted, with both showing some efficacy in managing PMS-related psychological symptoms. Herbal supplements like evening primrose oil and curcumin demonstrated mixed results and warrant additional research. The review also highlighted the influence of dietary patterns, showing Western diets rich in processed foods and refined sugars positively associate with increased PMS symptoms, whereas traditional and healthy diets rich in fruits, vegetables, and whole foods correlate with reduced symptom severity.
What are the greatest implications of this review?
This review underscores the potential of nutritional therapy as a complementary approach to PMS symptom management. It calls for increased awareness among healthcare providers to educate women on adopting balanced dietary habits that may mitigate symptoms. Given the current limitations in evidence, it encourages personalized nutritional counseling and advocates for further research integrating microbiome and metabolomic insights to refine diet-based interventions. This can potentially facilitate the development of microbiome-targeted dietary strategies to improve PMS and PMDD outcomes.
Premenstrual Syndrome (PMS)
Premenstrual Syndrome (PMS) involves physical and emotional symptoms linked to hormonal fluctuations. Recent research highlights the role of heavy metals and gut microbiome imbalances in worsening these symptoms. Lifestyle changes, microbiome-targeted therapies, and toxin reduction show promise in effective PMS management.
Premenstrual Dysphoric Disorder (PMDD)
Premenstrual Dysphoric Disorder (PMDD) is a severe mood disorder linked to hormonal and neurochemical changes. Emerging research highlights the gut microbiome’s role in symptom modulation, opening new avenues for microbiome-targeted treatments alongside traditional therapies.