Insight into Dysmenorrhea Research from 1992 to 2022: A Bibliometric Analysis Original paper
Researched by:
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Divine Aleru
ID
Divine Aleru
Read MoreI am a biochemist with a deep curiosity for the human microbiome and how it shapes human health, and I enjoy making microbiome science more accessible through research and writing. With 2 years experience in microbiome research, I have curated microbiome studies, analyzed microbial signatures, and now focus on interventions as a Microbiome Signatures and Interventions Research Coordinator.
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Women’s Health
Women’s Health
Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.
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Primary Dysmenorrhea
Primary Dysmenorrhea
Primary dysmenorrhea (PD) is painful menstrual cramps without underlying pelvic pathology, predominantly caused by elevated prostaglandins inducing uterine contractions and ischemia. Managing primary dysmenorrhea (PD) requires understanding its complex mechanisms involving prostaglandins, oxidative stress, and inflammation. Treatments include NSAIDs, hormonal therapies, and promising complementary options like probiotics, vitamins, omega-3 fatty acids, exercise, yoga, acupuncture, and massage, significantly improving women's quality of life.
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Divine Aleru
Read More
Researched by:
-
Divine Aleru
ID
Divine Aleru
Read More
Microbiome Signatures identifies and validates condition-specific microbiome shifts and interventions to accelerate clinical translation. Our multidisciplinary team supports clinicians, researchers, and innovators in turning microbiome science into actionable medicine.
Divine Aleru
What was studied?
This bibliometric analysis explores the global research trends and developments in dysmenorrhea over the past 30 years (1992-2022). The study investigates a broad range of publications from the Web of Science, focusing on the pathogenesis, treatment, and self-management strategies for primary dysmenorrhea (PD). The review categorizes the research into major themes, including the epidemiology of the condition, its associated risk factors, and the emerging focus on functional connectivity within the brain’s neural networks. The paper also highlights significant contributions from traditional Chinese medicine (TCM) in treating dysmenorrhea, such as acupuncture and moxibustion.
Who was studied?
The analysis includes global studies on dysmenorrhea, with a particular focus on research originating from China, the United States, and Iran. The study investigates a variety of dysmenorrhea-related factors such as pathogenesis, treatment effectiveness, and the prevalence of PD across different age groups, notably in women aged 17–24. The research also explores self-management practices among women experiencing dysmenorrhea, including lifestyle changes, herbal treatments, and the use of non-pharmacological interventions like heating pads and exercise.
Most important findings
The study shows that prostaglandins, specifically PGF2α and PGE2, are widely recognized as the primary mediators in the pathogenesis of PD, causing painful uterine contractions. Functional connectivity studies have become an emerging area of research, linking dysmenorrhea with structural and functional changes in brain regions involved in pain processing. The bibliometric analysis reveals a steady increase in publications related to dysmenorrhea, particularly from China and the United States. Notably, NSAIDs continue to be the most common pharmacological treatment, although a growing body of research supports the use of traditional Chinese medicine, including acupuncture and herbal treatments, as adjunctive therapies. The most significant recent keyword trends include “functional connectivity,” “endometriosis,” and “herbal medicine.”
Key implications
The increasing volume of research on dysmenorrhea highlights the global attention given to this common condition, with particular emphasis on understanding its pathophysiology and effective treatments. The role of traditional Chinese medicine is gaining recognition, but further clinical evidence is needed to substantiate its efficacy compared to conventional treatments. Given the varying prevalence rates, especially in young women, clinicians should consider individualized treatment strategies, including both pharmacological and non-pharmacological options. More research is needed to explore the mechanisms of functional connectivity and its relationship with pain sensitivity in dysmenorrhea.
Primary Dysmenorrhea
Primary dysmenorrhea (PD) is painful menstrual cramps without underlying pelvic pathology, predominantly caused by elevated prostaglandins inducing uterine contractions and ischemia. Managing primary dysmenorrhea (PD) requires understanding its complex mechanisms involving prostaglandins, oxidative stress, and inflammation. Treatments include NSAIDs, hormonal therapies, and promising complementary options like probiotics, vitamins, omega-3 fatty acids, exercise, yoga, acupuncture, and massage, significantly improving women's quality of life.
Endometriosis
Endometriosis involves ectopic endometrial tissue causing pain and infertility. Validated and Promising Interventions include Hyperbaric Oxygen Therapy (HBOT), Low Nickel Diet, and Metronidazole therapy.