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Autoimmune Diseases Brain Health Cardiovascular Health Metals Microbes Women’s Health

Conditions

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Alzheimer’s Dementia Anemia Autism spectrum disorder (ASD) Bacterial Vaginosis Breast Cancer Chronic Pelvic Pain (CPP) Diabetes Type I Endometriosis Erectile Dysfunction Female Infertility Graves Disease Hashimoto’s Thyroiditis Heart Failure Infertility Irritable Bowel Syndrome (IBS)

Definitions

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Amsel Criteria Blood-Brain Barrier (BBB) Bradford Hill Criteria Coelomic Metaplasia Theory Drug Repurposing  Endometriomas Environmental Theory of Endometriosis Estrobolome Estrogen Estrogen Receptors (ER) Facultative Anaerobes Fecal Microbiota Transplantation (FMT) Genetic and Epigenetic Theory of Disease Gram-Negative Bacteria Idiopathic

Guides & Resources

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Endometriosis Guide Microbiome Diet for Endometriosis

Interventions

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Boric Acid Cholestyramine Clindamycin Clinoptilolite Zeolite Dimethylglyoxime (DMG) Hyperbaric Oxygen Therapy (HBOT) Lactoferrin Low‑Nickel Diet (LNiD) Lugdunin Metformin Metronidazole Phage Therapy Photobiomodulation Probiotics Tinidazole

Supplements

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Essential Oils Flavones and Flavonols Guar Gum Pueraria Flower Extract (PFE)

Microbes

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Escherichia coli (E. coli) H pylori Pseudomonas aeruginosa Staphylococcus aureus (S. Aureus) Streptococcus agalactiae (GBS) Streptococcus spp. Ureaplasma urealyticum (U. urealyticum)

Metals

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Gallium Metalloestrogens Nickel Nickel in Escherichia coli: Metabolic and Pathogenic Roles Zinc

Research Feeds

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Structured Exercise Benefits in Euthyroid Graves’ Disease: Improved Capacity, Fatigue, and Relapse Maternal Iron Deficiency Anemia Affects Postpartum Emotions and Cognition Evidence for the Use of Complementary and Alternative Medicine for Pelvic Inflammatory Disease: A Literature Review The Effects of Toxic Heavy Metals Lead, Cadmium and Copper on the Epidemiology of Male and Female Infertility POI: Premature Ovarian Insufficiency/Pregnancy or Infertility? Pelvic inflammatory disease: a family practice perspective Microbiology profile in women with pelvic inflammatory disease in relation to IUD use Epidermiological markers in pelvic inflammatory disease (PID) among the women of reproductive age group Pelvic inflammatory disease and infertility Potential biomarkers of infertility associated with microbiome imbalances Bacterial isolates associated with pelvic inflammatory disease among female patients attending some hospitals in abuja, Nigeria Potential for Phages in the Treatment of Bacterial Sexually Transmitted Infections The relationship between polycystic ovary syndrome and infertility: a bibliometric analysis. The Key Element Role of Metallophores in the Pathogenicity and Virulence of Staphylococcus aureus: A Review Metformin as a Potential Treatment Option for Endometriosis

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March 17, 2025

  • Brain Health
    Brain Health

    Brain health encompasses the overall functioning and well-being of the brain, including cognitive function, emotional and psychological well-being, neurological integrity, behavioral health, neurodevelopmental health, age-related brain health, and brain resilience and plasticity.

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Last Updated: 2025

Microbiome Signatures identifies and validates condition-specific microbiome shifts and interventions to accelerate clinical translation. Our multidisciplinary team supports clinicians, researchers, and innovators in turning microbiome science into actionable medicine.

Karen Pendergrass

Karen Pendergrass is a microbiome researcher specializing in microbiome-targeted interventions (MBTIs). She systematically analyzes scientific literature to identify microbial patterns, develop hypotheses, and validate interventions. As the founder of the Microbiome Signatures Database, she bridges microbiome research with clinical practice. In 2012, based on her own investigative research, she became the first documented case of FMT for Celiac Disease—four years before the first published case study.

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