The magnitude of postpartum depression among mothers in Africa: a literaturereview Original paper

Researched by:

  • Divine Aleru ID
    Divine Aleru

    User avatarI am a biochemist with a deep curiosity for the human microbiome and how it shapes human health, and I enjoy making microbiome science more accessible through research and writing. With 2 years experience in microbiome research, I have curated microbiome studies, analyzed microbial signatures, and now focus on interventions as a Microbiome Signatures and Interventions Research Coordinator.

June 10, 2025

  • Women’s Health
    Women’s Health

    Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.

  • Postpartum Depression (PPD)
    Postpartum Depression (PPD)

    OverviewPostpartum depression (PPD) is a significant mental health issue affecting 13-19% of women globally within the first year after childbirth.[1][2] It is characterized by symptoms such as persistent sadness, anxiety, fatigue, and irritability. PPD not only impacts the mother’s mental health but also poses risks to infant development, including attachment issues, growth impairment, and behavioral […]

Researched by:

  • Divine Aleru ID
    Divine Aleru

    User avatarI am a biochemist with a deep curiosity for the human microbiome and how it shapes human health, and I enjoy making microbiome science more accessible through research and writing. With 2 years experience in microbiome research, I have curated microbiome studies, analyzed microbial signatures, and now focus on interventions as a Microbiome Signatures and Interventions Research Coordinator.

Last Updated: 2025

Microbiome Signatures identifies and validates condition-specific microbiome shifts and interventions to accelerate clinical translation. Our multidisciplinary team supports clinicians, researchers, and innovators in turning microbiome science into actionable medicine.

Divine Aleru

I am a biochemist with a deep curiosity for the human microbiome and how it shapes human health, and I enjoy making microbiome science more accessible through research and writing. With 2 years experience in microbiome research, I have curated microbiome studies, analyzed microbial signatures, and now focus on interventions as a Microbiome Signatures and Interventions Research Coordinator.

What was reviewed?

This is a literature review examining the magnitude of postpartum depression (PPD) among mothers in Africa. The review compiled findings from 21 research articles to analyze the prevalence of PPD across various African countries. It assessed studies that used different diagnostic tools, including the Edinburgh Postnatal Depression Scale (EPDS), Patient Health Questionnaire (PHQ-9), and others. The review also highlighted the challenges that inconsistent data poses, including the absence of locally validated diagnostic tools for screening PPD.

Who was reviewed?

The review focused on research studies that assessed postpartum depression in African mothers. The studies included postpartum women aged 17-49 years, who attended healthcare facilities for routine care or immunization. These studies were conducted across various African countries, such as Uganda, Nigeria, Morocco, and South Africa. The reviewed studies utilized a range of diagnostic tools, including the EPDS, PHQ-9, Kessler Scale (K10), and others. Still, they also noted the lack of validation of these tools in local African languages and cultural contexts.

What were the most important findings?

The review revealed considerable variation in the prevalence of postpartum depression across different African countries. For example, studies that used the EPDS found PPD rates ranging from 6.9% in Morocco to 43% in Uganda. Other tools, like the PHQ-9 and Kessler scales, reported prevalence rates ranging from 6.1% to 44%. These findings emphasize that PPD is a significant public health issue in Africa, with higher rates than in many developed countries. The review also highlighted that the EPDS tool was effective in diagnosing PPD in the African context, with sensitivity and specificity results ranging from 75% to 100% and 87% to 98%, respectively. However, the review also pointed out that many studies did not validate their assessment tools for local African languages or cultural settings, which could affect the accuracy of the diagnoses.

What are the greatest implications of this review?

The review underscores the need for culturally sensitive and locally validated diagnostic tools for assessing postpartum depression in African countries. The high prevalence rates of PPD suggest that it is an underrecognized and neglected public health issue. Clinicians in Africa should be encouraged to incorporate routine screening for PPD in postpartum care, using tools that are both reliable and contextually appropriate. This review calls for more research and policy initiatives to address the mental health needs of postpartum women in Africa, emphasizing the importance of early identification, treatment, and ongoing support. Additionally, the review stresses the need for a uniform approach to screening, ensuring that assessment tools are validated for the diverse cultural settings across the continent.

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