STOP: Routine Consumption of Hibiscus Tea/Juice and Its Potential Impact on Female Fertility

Researched by:

  • Divine Aleru ID
    Divine Aleru

    User avatarI am a biochemist with a deep curiosity for the human microbiome and how it shapes human health, and I enjoy making microbiome science more accessible through research and writing. With 2 years experience in microbiome research, I have curated microbiome studies, analyzed microbial signatures, and now focus on interventions as a Microbiome Signatures and Interventions Research Coordinator.

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July 22, 2025

Routine consumption of hibiscus tea or juice may affect female fertility by disrupting ovulation, implantation, and hormonal balance. Women trying to conceive or undergoing fertility treatments should be cautious and discuss herbal intake with their healthcare provider to avoid unintended reproductive consequences.

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Researched by:

  • Divine Aleru ID
    Divine Aleru

    User avatarI am a biochemist with a deep curiosity for the human microbiome and how it shapes human health, and I enjoy making microbiome science more accessible through research and writing. With 2 years experience in microbiome research, I have curated microbiome studies, analyzed microbial signatures, and now focus on interventions as a Microbiome Signatures and Interventions Research Coordinator.

    Read More

Last Updated: 2025-07-22

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Divine Aleru

I am a biochemist with a deep curiosity for the human microbiome and how it shapes human health, and I enjoy making microbiome science more accessible through research and writing. With 2 years experience in microbiome research, I have curated microbiome studies, analyzed microbial signatures, and now focus on interventions as a Microbiome Signatures and Interventions Research Coordinator.

Overview

Hibiscus tea, widely consumed for its antioxidant and health-promoting properties, contain bioactive compounds that may influence female reproductive health.[1][2] Emerging evidence suggests that routine intake of hibiscus products could modulate hormone balance and infertility by impacting ovarian function, implantation, and hormonal regulation, warranting cautious evaluation of their use during reproductive years.[3]

How Hibiscus Juice May Impact Female fertility

Hibiscus rosa-sinensis is a globally popular ornamental and medicinal plant whose flowers are commonly brewed into teas and juices prized for their antioxidant, antihypertensive, and anti-inflammatory effects.[4] Traditionally used in various cultures for reproductive health, hibiscus extracts have shown antifertility effects in preclinical studies, particularly in rodents.[5] Given the increasing popularity of hibiscus tea as a natural health beverage, understanding its potential influence on female fertility is critical, especially for women actively trying to conceive or undergoing fertility treatments.

1. Antiovulatory Effects

Extracts from H. rosa-sinensis flowers and roots have been shown to disrupt the estrous cycle by prolonging specific phases and inducing follicular atresia, leading to anovulation.[6] This antiovulatory activity is dose-dependent and reversible, indicating interference with normal ovarian function that could delay or prevent conception.[7]

2. Estrogenic and Antiestrogenic Activities

Hibiscus extracts exert complex estrogenic effects; some studies demonstrate increased uterine weight and vaginal cytology changes consistent with estrogen stimulation, while others report antiestrogenic activity, including reduced uterine and ovarian weights in animal models. These dual effects suggest hibiscus may modulate estrogen receptor pathways, altering hormonal homeostasis crucial for fertility.[8][9]

3. Anti-implantation and Interceptive Activity

Hibiscus flower and root extracts inhibit blastocyst implantation by altering endometrial receptivity, possibly through disruption of capillary hyperpermeability and progesterone suppression.[10][11] This mechanism leads to failure of pregnancy establishment despite ovulation, representing a significant antifertility pathway.

4. Effects on Hormonal Balance and Luteolysis

Post-coital antifertility studies indicate hibiscus extracts can induce luteolysis, decrease progesterone levels, and increase uterine enzyme activity, all of which compromise the hormonal environment necessary to maintain early pregnancy.[12][13]

Implications and Recommendations for Clinical Practice

Given the evidence from preclinical studies and limited clinical reports, clinicians should advise caution regarding routine consumption of hibiscus tea or juice, especially for women planning to conceive or undergoing fertility treatments. Hibiscus is recognized for its cardiovascular and antioxidant benefits, its potential antifertility effects, such as disruption of the estrous cycle, inhibition of ovulation, and impaired implantation, pose risks to female fertility. Hibiscus may interfere with hormonal treatments used in assisted reproductive technologies (ART), potentially reducing their effectiveness. Therefore, it is essential for women to disclose hibiscus intake to healthcare providers to ensure that its use does not inadvertently affect reproductive outcomes. Until further controlled clinical studies clarify safe dosage thresholds and identify populations at higher risk, healthcare professionals should recommend limiting or avoiding hibiscus consumption during conception attempts.

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Association between sex hormone levels and gut microbiota composition and diversity – A Systematic Review
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While estrogen is essential for normal bodily functions, excessive or prolonged exposure to estrogen, especially in hormone-sensitive tissues like the breast or uterus, can increase the risk of developing breast or endometrial cancer.

Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.

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Hibiscus Tea, Hormone Balance, and Thrombosis: A Case Report

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Contraceptive potential of Hibiscus rosa-sinensis (Linn.)
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Around 1 in 6 couples experience infertility, with the female factor contributing to about 35% of cases globally, according to a large multinational study by the World Health Organization (WHO).

Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.

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An update review on Hibiscus rosa sinensis phytochemistry and medicinal uses
October 10, 2018

Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.

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Herbal contraceptives: Evaluation of antifertility potential of Hibiscus rosa-sinensis (Linn.)
May 11, 2018
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Female Infertility
Female Infertility

Did you know?

Around 1 in 6 couples experience infertility, with the female factor contributing to about 35% of cases globally, according to a large multinational study by the World Health Organization (WHO).

Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.

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Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. roots
March 7, 2007
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Female Infertility
Female Infertility

Did you know?

Around 1 in 6 couples experience infertility, with the female factor contributing to about 35% of cases globally, according to a large multinational study by the World Health Organization (WHO).

Alias iure reprehenderit aut accusantium. Molestiae dolore suscipit. Necessitatibus eum quaerat. Repudiandae suscipit quo necessitatibus. Voluptatibus ullam nulla temporibus nobis. Atque eaque sed totam est assumenda. Porro modi soluta consequuntur veritatis excepturi minus delectus reprehenderit est. Eveniet labore ut quas minima aliquid quibusdam. Vitae possimus fuga praesentium eveniet debitis exercitationem deleniti.

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Female Infertility

Female infertility is a multifactorial condition affecting 10-15% of women of reproductive age, often caused by underlying conditions like Bacterial Vaginosis (BV), PCOS, Endometriosis, and Pelvic Inflammatory Disease (PID). Microbiome-targeted interventions (MBTIs) offer a promising approach to restoring balance, improving fertility outcomes, and addressing root causes.

Estrogen

Estrogen is a steroid hormone primarily found in women, crucial for reproductive health, secondary sexual characteristics, and various physiological processes. It regulates menstrual cycles, supports pregnancy, and influences bone density and cardiovascular health. Dysregulation of estrogen levels can lead to various disorders and health complications.

References

  1. An update review on Hibiscus rosa sinensis phytochemistry and medicinal uses.. Missoum A.. (J Ayurvedic Herb Med. 2018;4(3):135-146.)
  2. Herbal contraceptives: Evaluation of antifertility potential of Hibiscus rosa-sinensis (Linn.).. Chauhan SB, Naved T.. (Asian J Pharm Clin Res. 2018;11(11):36-41.)
  3. Contraceptive potential of Hibiscus rosa-sinensis (Linn.) – An update.. Gupta PC.. (Int J Pharm Res. 2012;4(4):133-137.)
  4. A Comprehensive Overview of Hibiscus rosa-sinensis L.: Its Ethnobotanical Uses, Phytochemistry, Therapeutic Uses, Pharmacological Activities, and Toxicology.. Amtaghri S, Qabouche A, Slaoui M, Eddouks M.. (Endocr Metab Immune Disord Drug Targets. 2024;24(1):86-115.)
  5. Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots. Vasudeva N, Sharma SK.. (Evid Based Complement Alternat Med. 2008;5(1):91-94.)
  6. Contraceptive potential of Hibiscus rosa-sinensis (Linn.) – An update.. Gupta PC.. (Int J Pharm Res. 2012;4(4):133-137.)
  7. Effect of benzene extract of Hibiscus rosa sinensis on the estrous cycle and ovarian activity in albino mice.. Murthy DR, Reddy CM, Patil SB.. (Biol Pharm Bull. 1997 Jul;20(7):756-8.)
  8. Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots. Vasudeva N, Sharma SK.. (Evid Based Complement Alternat Med. 2008;5(1):91-94.)
  9. Contraceptive potential of Hibiscus rosa-sinensis (Linn.) – An update.. Gupta PC.. (Int J Pharm Res. 2012;4(4):133-137.)
  10. Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots. Vasudeva N, Sharma SK.. (Evid Based Complement Alternat Med. 2008;5(1):91-94.)
  11. Flowers of Hibiscus rosa-sinensis, a potential source of contragestative agent: II. Possible mode of action with reference to anti-implantation effect of the benzene extract.. Pal AK, Bhattacharya K, Kabir SN, Pakrashi A.. (Contraception. 1985 Nov;32(5):517-29.)
  12. Herbal contraceptives: Evaluation of antifertility potential of Hibiscus rosa-sinensis (Linn.).. Chauhan SB, Naved T.. (Asian J Pharm Clin Res. 2018;11(11):36-41.)
  13. Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots. Vasudeva N, Sharma SK.. (Evid Based Complement Alternat Med. 2008;5(1):91-94.)

Amtaghri S, Qabouche A, Slaoui M, Eddouks M.

A Comprehensive Overview of Hibiscus rosa-sinensis L.: Its Ethnobotanical Uses, Phytochemistry, Therapeutic Uses, Pharmacological Activities, and Toxicology.

Endocr Metab Immune Disord Drug Targets. 2024;24(1):86-115.

Vasudeva N, Sharma SK.

Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots

Evid Based Complement Alternat Med. 2008;5(1):91-94.

Read Review

Vasudeva N, Sharma SK.

Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots

Evid Based Complement Alternat Med. 2008;5(1):91-94.

Read Review

Vasudeva N, Sharma SK.

Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots

Evid Based Complement Alternat Med. 2008;5(1):91-94.

Read Review

Vasudeva N, Sharma SK.

Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots

Evid Based Complement Alternat Med. 2008;5(1):91-94.

Read Review
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