Karen Pendergrass is a microbiome researcher specializing in microbiome-targeted interventions (MBTIs). She systematically analyzes scientific literature to identify microbial patterns, develop hypotheses, and validate interventions. As the founder of the Microbiome Signatures Database, she bridges microbiome research with clinical practice. In 2012, based on her own investigative research, she became the first documented case of FMT for Celiac Disease—four years before the first published case study.
2025-01-16 10:40:37
The influence of nickel on intestinal microbiota disturbancesExcess nickel disrupts gut microbiota, promoting dysbiosis and contributing to conditions like obesity and systemic nickel allergy syndrome (NAS). Probiotics and nickel-restricted diets show promise in mitigating these effects, underscoring the need for further research and clinical intervention.
2025-01-16 06:56:11
Potential Role of Copper in Diabetes and Diabetic Kidney DiseaseThis review explores copper’s role in diabetes and diabetic kidney disease, emphasizing its impact on oxidative stress, glycemic control, and renal function. Findings highlight the potential of copper homeostasis as a therapeutic target and the Cu ratio as a biomarker for diabetes management and KD progression.
2025-01-16 06:49:24
The Association between Zinc and Copper Circulating Levels and Cardiometabolic Risk Factors in Adults: A Study of Qatar Biobank DataThis study evaluated the associations of zinc, copper, and Cu ratio with cardiometabolic risk factors in Qatari adults, revealing copper’s protective role and Cu ratio’s adverse implications for metabolic health.
2025-01-16 06:39:35
The copper chelator ammonium tetrathiomolybdate inhibits the progression of experimental endometriosis in TNFR1-deficient miceAmmonium tetrathiomolybdate (M) inhibits endometriosis progression in NFR1-deficient mice by reducing copper and estradiol levels, lesion growth, angiogenesis, and oxidative stress.
2025-01-15 18:37:07
Exploring the link between dietary zinc intake and endometriosis risk: insights from a cross-sectional analysis of American womenThis study links higher dietary zinc intake with increased endometriosis risk among American women, highlighting zinc’s complex role in immune modulation and estrogen-related pathways. Findings emphasize the importance of balanced intake for managing endometriosis risk.
2025-01-15 18:18:39
Organophosphorus pesticide chlorpyrifos intake promotes obesity and insulin resistance through impacting gut and gut microbiotaChronic chlorpyrifos exposure induces obesity and insulin resistance by altering gut microbiota, increasing gut permeability, and driving inflammation.
2025-01-15 17:11:28
Nickel Allergy is Found in a Majority of Women with Chronic Fatigue Syndrome and Muscle Pain—and may be Triggered by Cigarette Smoke and Dietary Nickel IntakeNickel allergy, smoking, and dietary nickel intake may worsen chronic fatigue and muscle pain. Managing exposure can improve symptoms.
2025-01-15 16:54:56
The impact of endometriosis on dietary choices and activities of everyday life: a cross-sectional studyThis review highlights how gluten-free, Mediterranean, and anti-inflammatory diets improve pain perception in endometriosis by reducing inflammation and modulating the gut microbiome. Probiotics and bioactive nutrients such as curcumin enhance therapeutic outcomes.
2025-01-15 16:47:40
I Am the 1 in 10—What Should I Eat? A Research Review of Nutrition in EndometriosisThis review explores how dietary modifications impact endometriosis progression. Antioxidants, omega-3s, and anti-inflammatory diets show promise in symptom relief and hormonal regulation. Personalized nutrition emerges as a pivotal tool for improving patient outcomes.
2025-01-15 16:34:25
Elevated levels of whole blood nickel in a group of Sri Lankan women with endometriosis: a case control studyThis study identified elevated blood nickel levels in women with endometriosis, suggesting a potential role of nickel as a metalloestrogen in its pathogenesis.