Karen Pendergrass is a microbiome researcher specializing in microbiome-targeted interventions (MBTIs). She systematically analyzes scientific literature to identify microbial patterns, develop hypotheses, and validate interventions. As the founder of the Microbiome Signatures Database, she bridges microbiome research with clinical practice. In 2012, based on her own investigative research, she became the first documented case of FMT for Celiac Disease—four years before the first published case study.
2024-09-25 12:44:41
Major Microbial Associations (MMAs)Major Microbial Associations (MAs) are fundamental in understanding disease-microbiome interactions and play a crucial role in advancing microbiome-targeted interventions aimed at treating or preventing diseases through microbial modulation.
2024-09-24 12:28:53
Gram-Negative BacteriaGram-negative bacteria are resilient pathogens with antibiotic resistance, causing infections like TIs, sepsis, and pneumonia.
2024-09-24 10:20:32
Oxidase PositiveOxidase positivity in an organism refers to the ability of the organism to produce the enzyme cytochrome c oxidase, which is involved in the electron transport chain during aerobic respiration.
2024-09-18 11:43:23
Koch’s PostulatesOverview Koch’s postulates, formulated by Robert Koch in the late 19th century, were a set of criteria used to establish a causative relationship between a specific microbe and a disease. These postulates became foundational in microbiology, providing a systematic approach for identifying pathogenic microorganisms. The original postulates consist of four criteria:Presence of the Microbe in […]
2024-09-16 12:01:44
Nickel Allergic Contact Mucositis in Suspected Non-Responsive Celiac DiseaseThe study found that 100% of the D patients who completed the study tested positive for allergic contact mucositis to Nickel.
2024-09-16 11:21:20
Nickel Sensitivity in Endometriosis: Symptoms Management and The Role of a Low-Nickel DietThis study offers new insights into the potential link between nickel sensitivity and symptom severity in endometriosis, suggesting that a low-nickel diet may be a promising intervention for alleviating associated gastrointestinal and gynecological symptoms.
2024-09-16 10:08:45
Nickel Sensitivity in Patients With Irritable Bowel SyndromeThis study suggests that nickel sensitivity may play a significant role in the etiology of BS, warranting further exploration and potentially influencing future diagnostic and therapeutic strategies for BS management.
2024-08-10 16:34:51
The gut microbiota–brain axis in neurological disorderWhat was reviewed?The review paper provides a comprehensive overview of the gut microbiota-brain axis (BA) and its role in various neurological disorders. Specifically, the paper examined the intricate bidirectional communication between the gut microbiota (M) and the central nervous system (NS), exploring how dysbiosis (an imbalance in the gut microbiota) contributes to the pathogenesis of […]
2024-08-10 11:39:16
The gut microbiome in neurological disordersPathways of communication between the microbiota and the brain.
2024-08-10 11:11:03
Neuromicrobiology, an Emerging Neurometabolic Facet of the Gut Microbiome?What Was The paper reviews the emerging field of neuromicrobiology, which explores the interactions between the gut microbiome and the brain, particularly focusing on how gut microbiota produce neuroactive metabolites that influence cognitive function and brain health. It addresses the biosynthesis, absorption, and transport of these neuroactive metabolites, including neurotransmitters such as γ-aminobutyric acid (ABA), […]