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Karen Pendergrass, Standards Team

About

Karen Pendergrass is a microbiome researcher specializing in microbiome-targeted interventions (MBTIs). She systematically analyzes scientific literature to identify microbial patterns, develop hypotheses, and validate interventions. As the founder of the Microbiome Signatures Database, she bridges microbiome research with clinical practice. In 2012, based on her own investigative research, she became the first documented case of FMT for Celiac Disease—four years before the first published case study.

Recent Posts

2024-06-23 08:03:07

Coincidence of uterine malformations and endometriosis: a clinically relevant problem?

What was studied?The retrospective study explored the prevalence of endometriosis in patients with uterine malformations. It specifically investigated the relationship between different types of uterine malformations (obstructive, non-obstructive, and various classifications under the American Fertility Society (FS)) and the incidence of endometriosis, which is characterized by the presence of endometrial tissue outside the uterus. The […]

2024-06-23 08:03:07

Endometriosis of the lung: A case report and brief review of the literature

What was studied?The study focused on pulmonary endometriosis, a rare condition characterized by the presence of endometrial tissue in the lungs. It analyzed a series of historical and recent cases, dividing them into two distinct groups based on the characteristics of the lung lesions and their association with pregnancy and endometrial glands. The study aimed […]

2024-06-23 08:03:06

Meta-analysis of gut microbiome studies identifies disease-specific and shared responses

What was studied?The meta-analysis focused on the human gut microbiome’s association with various diseases by analyzing 28 published case-control gut microbiome studies covering ten diseases. The researchers aimed to standardize the processing and analysis of these datasets to identify consistent patterns and shifts in the gut microbiome associated with specific diseases or a generalized health-disease […]

2024-06-23 08:03:06

Müllerian duct anomalies coincident with endometriosis: a review

What was studied?The study reviewed the relationship between Müllerian duct anomalies (DAs) and endometriosis, focusing on their coexistence and the underlying pathophysiological theories that might explain their association. It extensively covered the embryology, genetics, and pathophysiology of DAs, alongside the American Society for Reproductive Medicine (SRM) classification of these anomalies. The review also detailed different […]

2024-06-23 08:03:05

Somatic stem cells and their dysfunction in endometriosis

What was studied?The study focused on the role of somatic stem cells (SCs), including endometrial stem cells (SCs) and bone marrow-derived mesenchymal stem cells (SCs), in the pathogenesis of endometriosis. This was conducted through a comprehensive literature review, including in vitro experiments and studies on animal models and human tissue analyses. The research examined the […]

2024-06-23 08:03:05

Epigenetics of endometriosis

What was studied?The review focused on the role of epigenetic changes in endometriosis, exploring how these modifications influence the disease’s etiopathogenesis, diagnosis, and therapeutic approaches. It reviewed existing evidence up to June 2009, linking epigenetic aberrations such as NA methylation and histone modification to endometriosis, and discussed the potential of these aberrations in developing non-surgical […]

2024-06-23 08:03:04

Endometrial whole metabolome profile at the receptive phase: influence of Mediterranean Diet and infertility

What was studied?The study focused on analyzing the receptive-phase endometrial metabolome profiles among women with infertility and examining their associations with adherence to the Mediterranean Diet (D). It aimed to identify metabolomic signatures that could influence the intrauterine environment and impact reproductive outcomes. Who was studied?The study involved 45 women of infertile couples, recruited at the […]

2024-06-23 08:03:03

Transvaginal Photobiomodulation for the Treatment of Chronic Pelvic Pain: A Pilot Study

The study in question focused on the use of transvaginal photobiomodulation (V-BM) as a treatment for chronic pelvic pain (PP) in women. Here are the details based on the key aspects of the study: What was studied?The research investigated whether transvaginal photobiomodulation could effectively reduce chronic pelvic pain in women. This was a pilot study aiming […]

2024-06-23 08:03:03

New Insights into Photobiomodulation of the Vaginal Microbiome—A Critical Review

What was studied?The study reviewed the potential effects of photobiomodulation (BM) on the vaginal microbiome, particularly exploring theoretical and emerging research on how BM may influence vaginal health through its interaction with microbial communities. Who was studied?The study itself is a review and does not directly study a group of individuals. Instead, it synthesizes research on […]