Karen Pendergrass, Standards Team

What was studied?The study focused on identifying and comparing the bacterial patterns present in the vaginal fluid, eutopic endometrium, and endometriotic lesions of patients with endometriosis to those found in the vaginal fluid and eutopic endometrium of control patients without the disease. High-throughput NA sequencing of the 16S rRNA marker gene was utilized to analyze […]

What was studied?The study aimed to investigate how endometriosis affects the uterine and cervical bacterial communities. Utilizing next-generation amplicon sequencing of the bacterial 16S rRNA gene, the research sought to identify alterations in these microbiomes associated with endometriosis and to determine if specific bacterial taxa within the cervix could help diagnose active endometriosis, potentially avoiding […]

This study reveals Anaerococcus as a predictive marker for endometriosis severity and highlights Lactobacillus crispatus’s lactic acid-mediated modulatory role, offering promise for non-invasive diagnostics.

What was studied?The study focused on exploring the associations between the microbiota of the vaginal, cervical, and gut regions and stage 3–4 endometriosis in women. This research aimed to uncover potential differences in the microbiome composition between women diagnosed with advanced endometriosis and healthy controls, particularly at the genus level of microbial classification. Who was studied?The […]

This study reveals that gut microbiota dysbiosis in immune-mediated inflammatory diseases includes shared enrichment of pro-inflammatory taxa like Streptococcus and Eggerthella, alongside depletion of beneficial genera such as Roseburia. These patterns support a common microbial signature across MIDs and highlight potential targets for diagnosis and therapeutic intervention.

What was studied?This study explored the gut microbiota of children diagnosed with early-onset pediatric multiple sclerosis (S) and compared it to controls of similar age and sex. The researchers aimed to identify gut microbial community differences, including taxonomic and functional perturbations, and examined the influence of immunomodulatory drug (MD) exposure. This study also predicted functional […]

This case-control study investigates the gut microbiota’s role in multiple sclerosis (S) pathogenesis by comparing the fecal microbiota of relapsing-remitting S patients to healthy controls. Findings reveal significant microbial dysbiosis in S patients, highlighting differences in the abundance of specific bacterial genera, supporting the gut microbiota’s involvement in S etiology.

What Was The study focused on the association between the composition of cervical microbiota and pregnancy outcomes in a subfertile population undergoing in vitro fertilization (VF). Specifically, it aimed to characterize the cervical microbiota of patients undergoing embryo transfer (T) and assess whether the composition of these microbiota is associated with the outcomes of the […]

What was studied?The study investigated the characteristics of gut microbiota in patients with asthenozoospermia (S), a common cause of male infertility characterized by reduced sperm motility. It aimed to identify differences in gut microbiota composition between S patients and healthy controls and explore the potential links between gut microbiota and the development of S. Who was […]

What was studied?The study investigated the differences in gut microbiota between men with erectile dysfunction (D) and healthy controls to identify key microbiota associated with D and explore the potential pathogenic role of specific bacteria.Who was studied?A total of 43 men diagnosed with D and 16 healthy controls, all of whom met specific inclusion criteria […]