Karen Pendergrass is a microbiome researcher specializing in microbiome-targeted interventions (MBTIs). She systematically analyzes scientific literature to identify microbial patterns, develop hypotheses, and validate interventions. As the founder of the Microbiome Signatures Database, she bridges microbiome research with clinical practice. In 2012, based on her own investigative research, she became the first documented case of FMT for Celiac Disease—four years before the first published case study.
2021-01-01 00:00:00
Gut microbiota imbalance and its correlations with hormone and inflammatory factors in patients with stage 3/4 endometriosisThis study explores the gut microbiota imbalance and its correlations with hormone and inflammatory factors in stage 3/4 endometriosis. Key findings reveal distinct microbial shifts linked to hormonal dysregulation and inflammation, offering insights into disease mechanisms and potential microbiome-targeted therapeutic approaches.
2021-01-01 00:00:00
Altered Composition of Microbiota in Women with Ovarian Endometrioma: Microbiome Analyses of Extracellular Vesicles in the Peritoneal Fluid2021-01-01 00:00:00
The role of the vaginal microbiome in distinguishing female chronic pelvic pain caused by endometriosis/adenomyosis2021-01-01 00:00:00
Altered Gut Microbiota in Irritable Bowel Syndrome and Its Association with Food ComponentsThis study explores the altered gut microbiota in BS and its association with caffeine and dietary fiber. Findings indicate that high caffeine intake is linked to increased microbial diversity and altered gut microbiome composition in BS patients, offering insights into dietary strategies for symptom modulation.
2021-01-01 00:00:00
Gut microbiota composition and functional prediction in diarrhea-predominant irritable bowel syndromeThis study reveals that gut microbiota in BS-D patients is characterized by reduced Firmicutes, Fusobacteria, and Actinobacteria, alongside elevated Proteobacteria. Functional predictions indicate disrupted metabolism and increased inflammatory pathways, suggesting microbiome-targeted interventions may benefit BS-D symptom management.
2021-01-01 00:00:00
Understanding of the Site-Specific Microbial Patterns towards Accurate Identification for Patients with Diarrhea-Predominant Irritable Bowel SyndromeThis study identifies site-specific microbial patterns in BS-D patients, highlighting Bacteroides, Prevotella, and Oscillospira in the rectal mucosa as biomarkers. Findings suggest that rectal mucosa sampling may enhance diagnostic accuracy, paving the way for personalized microbiome-based treatments for BS-D.
2021-01-01 00:00:00
Intestinal microbiota influences clinical outcome and side effects of early breast cancer treatment2021-01-01 00:00:00
Comprehensive profiles and diagnostic value of menopausal-specific gut microbiota in premenopausal breast cancer2021-01-01 00:00:00
Gut Microbiome Features of Chinese Patients Newly Diagnosed with Alzheimer’s Disease or Mild Cognitive Impairment2021-01-01 00:00:00
APOE-ε4 Carrier Status and Gut Microbiota Dysbiosis in Patients With Alzheimer Disease