Research Feeds

View All
1H NMR- based metabolomics approaches as non-invasive tools for diagnosis of endometriosis A Comparative Study of Blood Levels of Manganese, Some Macroelements and Heavy Metals in Obese and Non-Obese Polycystic Ovary Syndrome Patients A Comparative Study of the Gut Microbiota Associated With Immunoglobulin a Nephropathy and Membranous Nephropathy A comparative study of the gut microbiota in immune-mediated inflammatory diseases-does a common dysbiosis exist? A comprehensive analysis of breast cancer microbiota and host gene expression A comprehensive analysis of breast cancer microbiota and host gene expression A cross-sectional analysis about bacterial vaginosis, high-risk human papillomavirus infection, and cervical intraepithelial neoplasia in Chinese women A cross-sectional pilot study of birth mode and vaginal microbiota in reproductive-age women A metabonomics approach as a means for identification of potentialbiomarkers for early diagnosis of endometriosis A More Diverse Cervical Microbiome Associates with Better Clinical Outcomes in Patients with Endometriosis: A Pilot Study A Multi-Omic Systems-Based Approach Reveals Metabolic Markers of Bacterial Vaginosis and Insight into the Disease A New Approach to Polycystic Ovary Syndrome: The Gut Microbiota A Review of the Anti-inflammatory Properties of Clindamycin in the Treatment of Acne Vulgaris A Systematic Review and Meta-Analysis of Premenstrual Syndrome with Special Emphasis on Herbal Medicine and Nutritional Supplements. Adherence to the Mediterranean Diet, Dietary Patterns and Body Composition in Women with Polycystic Ovary Syndrome (PCOS)
women's health microbiome

Women’s Health

August 15, 2024

Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. Signatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.

Last Updated: March 22, 2024

Microbiome Signatures identifies and validates condition-specific microbiome shifts and interventions to accelerate clinical translation. Our multidisciplinary team supports clinicians, researchers, and innovators in turning microbiome science into actionable medicine.

Karen Pendergrass

Karen Pendergrass is a microbiome researcher specializing in microbiome-targeted interventions (MBTIs). She systematically analyzes scientific literature to identify microbial patterns, develop hypotheses, and validate interventions. As the founder of the Microbiome Signatures Database, she bridges microbiome research with clinical practice. In 2012, based on her own investigative research, she became the first documented case of FMT for Celiac Disease—four years before the first published case study.

Women’s health, a vital aspect of medical science, encompasses various conditions unique to women’s physiological makeup. Historically, women were often excluded from clinical research, leading to a gap in understanding the intricacies of women’s health needs. However, recent advancements have highlighted the significant role that the microbiome plays in these conditions, offering new insights and potential therapies. MicrobiomeSignatures.com is at the forefront of exploring the microbiome signature of each of these conditions to unravel the etiology of these diseases and develop targeted microbiome therapies.

What is Women’s Health?

Women’s health involves a spectrum of conditions ranging from breast and cervical cancers to hormonal disorders like polycystic ovary syndrome (PCOS) and menopause. It also covers issues such as infertility, dysmenorrhea, and various sexual health concerns. While most research historically has focused on cisgender women, the scope of study often extends to transgender and nonbinary individuals, particularly concerning conditions related to shared biological structures.

Healthcare Providers and Women’s Health

For specific women’s health concerns, consulting an obstetrician/gynecologist (OB/GYN) is recommended. These specialists focus on the female reproductive system, pregnancy, and overall women’s health. However, women may seek care from various specialists for other health issues.

Importance of Health Screening

Regular health screenings like Pap smears, bone density tests, breast exams, and immunizations are crucial for early detection of potential health problems. The frequency of these screenings varies based on age, health history, and individual risk factors.

Unique Health Challenges for Women

Women’s health issues are sometimes underdiagnosed due to historical underrepresentation in medical research. For example, heart attack symptoms in women can be subtler compared to men, often leading to delayed diagnosis and treatment. Thus, increased representation in research is essential for better health outcomes.

Women’s Health Conditions and the Microbiome

The microbiome’s role in women’s health is a groundbreaking study area. MicrobiomeSignatures.com is dedicated to understanding the microbiome signature in conditions like Bacterial Vaginosis, Breast Cancer, Cervical Cancer, Endometriosis, PCOS, Menopause, Infertility, and others. By analyzing these signatures, we aim to unlock a better understanding of the diseases’ etiology and develop targeted microbiome therapies.

Condition/GoalStatus
Bacterial Vaginosis (BV)Unfinished
Breast CancerUnfinished
Breast EngorgementUnfinished
Breast PainUnfinished
CelluliteUnfinished
Cervical CancerUnfinished
Endometrial CancerUnfinished
EndometriosisFinished
Female Sexual DysfunctionUnfinished
Hormone HealthUnfinished
Hot FlashesUnfinished
Hypoactive Sexual Desire DisorderUnfinished
InfertilityUnfinished
MastitisUnfinished
Menopausal SymptomsUnfinished
MenopauseUnfinished
Menstrual HealthUnfinished
Ovarian CancerUnfinished
Polycystic Ovary Syndrome (PCOS)Unfinished
Premenstrual Dysphoric Disorder (PMDD)Unfinished
Premenstrual Syndrome (PMS)Unfinished
Primary Dysmenorrhea (Menstrual Cramps)Unfinished
Primary Ovarian InsufficiencyUnfinished
Rett Syndrome (RTT)Unfinished
Sexual DysfunctionUnfinished
Sexual HealthUnfinished
SubfertilityUnfinished
Takayasu’s ArteritisUnfinished
Vaginal HealthUnfinished
Vulvovaginal Candidiasis (Yeast Infection)Unfinished

Women’s health is a complex and multifaceted field. By delving into the microbiome’s role, MicrobiomeSignatures.com aims to contribute significantly to understanding and treating women’s health conditions. This approach could revolutionize how we view and manage these conditions, leading to more effective and personalized treatments. As we continue to explore these connections, our goal is to enhance health outcomes and quality of life for women worldwide.

Endometriosis

Endometriosis involves ectopic endometrial tissue causing pain and infertility. Validated and Promising Interventions include Hyperbaric Oxygen Therapy (HBOT), Low Nickel Diet, and Metronidazole therapy.

Endometriosis

Endometriosis involves ectopic endometrial tissue causing pain and infertility. Validated and Promising Interventions include Hyperbaric Oxygen Therapy (HBOT), Low Nickel Diet, and Metronidazole therapy.

Join the Roundtable

Contribute to published consensus reports, connect with top clinicians and researchers, and receive exclusive invitations to roundtable conferences.