Microbial Metallomics
Researched by:
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Karen Pendergrass
ID
Karen Pendergrass
Karen Pendergrass is a microbiome researcher specializing in microbiome-targeted interventions (MBTIs). She systematically analyzes scientific literature to identify microbial patterns, develop hypotheses, and validate interventions. As the founder of the Microbiome Signatures Database, she bridges microbiome research with clinical practice. In 2012, based on her own investigative research, she became the first documented case of FMT for Celiac Disease—four years before the first published case study.
Microbial Metallomics is the study of how microorganisms interact with metal ions in biological systems, particularly within the human microbiome.
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Karen Pendergrass
Researched by:
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Karen Pendergrass
ID
Karen Pendergrass
Microbiome Signatures identifies and validates condition-specific microbiome shifts and interventions to accelerate clinical translation. Our multidisciplinary team supports clinicians, researchers, and innovators in turning microbiome science into actionable medicine.
Karen Pendergrass
Overview Overview
Microbial Metallomics is the study of how microorganisms interact with metal ions in biological systems, particularly within the human microbiome. This field examines the role of metals as cofactors in microbial metabolism, virulence, and competitive survival strategies, as well as how microbial communities influence metal bioavailability, sequestration, and toxicity. By integrating microbiology, biochemistry, and bioinorganic chemistry, Microbial Metallomics provides insights into microbial metal homeostasis, host-pathogen interactions, and the impact of metal disturbances on health and disease.